“…Magnetic capture and separationsSuperparamagnetic nanomaterials are becoming a promising tool for the capture, concentration, isolation, and separation of biomolecules such as in vitro cells, antibodies, proteins, DNA, enzymes, bacteria, and different pathogens from their complex biological matrixes 29,66,151. MNPs offer several significant advantages over conventional separation techniques such as chromatography: they possess a large surface-to-volume ratio, are readily dispersible in solution, can be quickly localized or retrieved using a typical external magnet, and provide high versatility and reusability of NPs after the magnetic separation 152. Generally, MNPs are functionalized with different surfactants, polymers, and ligands to introduce functional end groups such as -OH, -NH2, -COOH, and -SH for the selective capturing of target biomolecules.…”