Continuous minimally-invasive alcohol monitoring using microneedle sensor arrays

Mohan, A. M. Vinu; Windmiller, Joshua Ray; Mishra, Rupesh K.; Wang, Joseph

doi:10.1016/j.bios.2017.01.016

Cited by 206 publications

(164 citation statements)

References 34 publications

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“…Noninvasive, (multi)parameter chemical analysis of ions or conductivity, trace metals, pH, alcohol, lactate, or glucose in sweat is another area of application for wearable sensors. Among them, glucose is by far the most important analyte since for diabetics and athletics the close monitoring of glucose levels is crucial and therefore, this has been a major focal point in wearables research.…”

Section: Fields Of Applicationmentioning

confidence: 99%

Disposable Sensors in Diagnostics, Food, and Environmental Monitoring

et al. 2019

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Disposable sensors are low‐cost and easy‐to‐use sensing devices intended for short‐term or rapid single‐point measurements. The growing demand for fast, accessible, and reliable information in a vastly connected world makes disposable sensors increasingly important. The areas of application for such devices are numerous, ranging from pharmaceutical, agricultural, environmental, forensic, and food sciences to wearables and clinical diagnostics, especially in resource‐limited settings. The capabilities of disposable sensors can extend beyond measuring traditional physical quantities (for example, temperature or pressure); they can provide critical chemical and biological information (chemo‐ and biosensors) that can be digitized and made available to users and centralized/decentralized facilities for data storage, remotely. These features could pave the way for new classes of low‐cost systems for health, food, and environmental monitoring that can democratize sensing across the globe. Here, a brief insight into the materials and basics of sensors (methods of transduction, molecular recognition, and amplification) is provided followed by a comprehensive and critical overview of the disposable sensors currently used for medical diagnostics, food, and environmental analysis. Finally, views on how the field of disposable sensing devices will continue its evolution are discussed, including the future trends, challenges, and opportunities.

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Section: Fields Of Applicationmentioning

confidence: 99%

Disposable Sensors in Diagnostics, Food, and Environmental Monitoring

et al. 2019

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“…Due to this mechanism, ISF alcohol levels display a close correlation with concurrent concentrations in blood [22]. Wang et al developed a microneedle-based minimally-invasive sensing platform for analyzing alcohol concentrations in ISF (Figure 3B) [42]. Microneedles readily access the ISF to facilitate transdermal monitoring.…”

Section: Isf-based Alcohol Detectionmentioning

confidence: 99%

Wearable electrochemical alcohol biosensors

Campbell

Kim

Wang

2018

Current Opinion in Electrochemistry

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106

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The rapid development of wearable sensing platforms in recent years has led to an array of viable monitoring applications for various target analytes. As a significant biomarker with high impact in diverse areas, the reliable on-body detection and continuous monitoring of alcohol has become a focus of many such systems. Currently, several commercial sensing platforms are available that are capable of transdermal monitoring of alcohol consumption using insensible sweat. Drawbacks of existing alcohol sensing platforms that apply this sensing strategy have led to efforts in developing wearable biosensors capable of real-time alcohol detection in sampled biofluids such as sensible sweat and skin interstitial fluid. This review discusses the current trends in wearable electrochemical alcohol biosensing and highlights recent advances in such systems toward continuous, real-time monitoring of alcohol consumption. Our perspective on this important field is given with an outlook on the future of wearable electrochemical alcohol biosensors.

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“…In these cases, the enzymes were dispersed in a carbon paste matrix serving as an electrode, generating a signal used for analyte quantification. The strategy has also been proposed for continuously monitoring blood alcohol level, following the findings that ISF ethanol concentration is strongly correlated with ethanol concentration in the blood …”

Section: Mns For In Situ Analyte Monitoringmentioning

confidence: 99%

Advances in the Design of Transdermal Microneedles for Diagnostic and Monitoring Applications

Babity

Roohnikan

Brambilla

2018

Small

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Due to their intrinsic advantages over classical hypodermic needles, microneedles have received much attention over the last two decades and will likely soon appear in clinics. Although the vast majority of research is focused on designing microneedles for the painless delivery of drugs, their applications for diagnostic purposes have also provided promising results. In this paper, the main advances in the field of microneedles for diagnostic and patient monitoring purposes are introduced and critically discussed.

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Continuous minimally-invasive alcohol monitoring using microneedle sensor arrays

Cited by 206 publications

References 34 publications

Disposable Sensors in Diagnostics, Food, and Environmental Monitoring

Disposable Sensors in Diagnostics, Food, and Environmental Monitoring

Wearable electrochemical alcohol biosensors

Advances in the Design of Transdermal Microneedles for Diagnostic and Monitoring Applications

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