“…Hop-related dermatitis has presented as airborne dermatitis, hand dermatitis, and pruritus, 12 facial dermatitis and conjunctivitis, 13,14 and contact urticaria. 14 There is recognition within the hop-growing region in Washington State that hop dust is an allergen. Acknowledging that cases occurred throughout nearly all phases of hop harvest, including indirect exposure, underscores either the combined or independent effect of dust pervasiveness and/or dust potency.…”
Occupational exposure to hop dust is associated with respiratory disease. Respiratory disease rates were higher in hop workers than in a comparison group of agricultural workers. Additional research is needed before hop dust can be confirmed as a causative agent for occupational asthma.
“…Hop-related dermatitis has presented as airborne dermatitis, hand dermatitis, and pruritus, 12 facial dermatitis and conjunctivitis, 13,14 and contact urticaria. 14 There is recognition within the hop-growing region in Washington State that hop dust is an allergen. Acknowledging that cases occurred throughout nearly all phases of hop harvest, including indirect exposure, underscores either the combined or independent effect of dust pervasiveness and/or dust potency.…”
Occupational exposure to hop dust is associated with respiratory disease. Respiratory disease rates were higher in hop workers than in a comparison group of agricultural workers. Additional research is needed before hop dust can be confirmed as a causative agent for occupational asthma.
“…Case reports of irritation and sensitization to Humulus lupulus (hops) or the constituent β-myrcene while working with the plant on farms, laboratories, and in breweries are recited in Table 14. 11,54,[104][105][106] Summary This is a safety assessment of Humulus Lupulus (Hops) Extract and Humulus Lupulus (Hops) Oil as used in cosmetics. Both of these ingredients are derived from the strobile of the Humulus lupulus plant, commonly called hops.…”
Section: Case Reportsmentioning
confidence: 99%
“…Humulus lupulus (hops) plants are reported to contain linalool, quercetin, β-myrcene, 8-PN (or hopein), and other prenylated flavonoids (Figure 1). 42,43,52,54-56 Humulus lupulus (hops) oil is reported to contain sesquiterpene lactones. 17,50-52 The potential adverse effects of exposures to these constituents are summarized in Table 10.Figure 1.Constituents of concern of Humulus lupulus (hops) plants.…”
The Expert Panel for Cosmetic Ingredient Safety (Panel) assessed the safety of Humulus Lupulus (Hops) Extract (reported functions include antimicrobial agent and hair conditioning agent) and Humulus Lupulus (Hops) Oil (reported function is fragrance). The Panel reviewed the relevant data related to these ingredients. Because final product formulations may contain multiple botanicals, each containing the same constituents of concern, formulators are advised to be aware of these constituents and to avoid reaching levels that may be hazardous to consumers. For these ingredients, the Panel was concerned about the presence of 8-prenylnaringenin, β-myrcene, and quercetin in cosmetics, which could result in estrogenic effects, dermal irritation, and genotoxicity, respectively. Industry should use current good manufacturing practices to limit impurities and constituents of concern. The Panel concluded that Humulus Lupulus (Hops) Extract and Humulus Lupulus (Hops) Oil are safe in cosmetics in the present practices of use and concentration when formulated to be non-sensitizing.
“…A further case has been described of a patient who complained of urticaria on both hands while working with ripe dried hops, although not with fresh ones. Type 1 allergy was confirmed by prick test and specific IgE.…”
Section: Plant Sources Of Some European Herbal Medicinal Products Andmentioning
SummaryThis review focuses on contact dermatitis as an adverse effect of a selection of topically used herbal medicinal products for which the European Medicines Agency has completed an evaluation up to the end of November 2013 and for which a Community herbal monograph has been produced. Part 2: Echinacea purpurea Moench-Lavandula angustifolia Mill.
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