Contact dermatitis as an adverse reaction to some topically used European herbal medicinal products – Part 2: <i>Echinacea purpurea–Lavandula angustifolia</i>

Gangemi, Sebastiano; Minciullo, Paola Lucia; Miroddi, Marco; Chinou, İoanna; Calapai, Gioacchino; Schmidt, Richard J.

doi:10.1111/cod.12328

Cited by 20 publications

(21 citation statements)

References 99 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In Patch-testing for contact allergy to lavender oil addition, photoallergic contact dermatitis to lavender oil in topical ketoprofen preparations has been reported (37). Also, the interest in essential oils, such as lavender oil, in alternative medicine is increasing (2,3,5) and several studies show that exposure to botanically derived products and natural drugs, based on plant extracts and essential oils can be causes of allergic contact dermatitis (38)(39)(40). Thus, allergic contact dermatitis to essential oils mirrors the broad spectrum of use of these plant extracts, and exposures beyond aromatherapy and fragranced cosmetic products are of importance.…”

Section: Discussionmentioning

confidence: 99%

Patch Testing with Main Sensitizers Does Not Detect All Cases of Contact Allergy to Oxidized Lavender Oil

Hagvall¹,

Christensson²

2016

Acta Derm Venerol

View full text Add to dashboard Cite

Lavender oil is an essential oil obtained from lavender (Lavendula angustifolia). The main components linalool and linalyl acetate have been shown to autoxidize in contact with oxygen in the air, forming sensitizing hydroperoxides. Patients with suspected allergic contact dermatitis were consecutively patch-tested with oxidized lavender oil 6% pet., oxidized linalyl acetate 6% pet., and oxidized linalool 6% pet. to investigate the frequency of contact allergy to oxidized lavender oil, and the pattern of concomitant reactions to oxidized linalool and oxidized linalyl acetate. Positive reactions to oxidized lavender oil were found in 2.8% of the patients. Among those, 56% reacted to oxidized linalool and/or oxidized linalyl acetate, while 52% reacted to the fragrance markers of the baseline series. Oxidized lavender oil showed among the highest frequencies of contact allergy to studied essential oils. A well-standardized preparation of oxidized lavender oil could be a useful tool for diagnosis of contact allergy to fragrances.

show abstract

Section: Discussionmentioning

confidence: 99%

Patch Testing with Main Sensitizers Does Not Detect All Cases of Contact Allergy to Oxidized Lavender Oil

Hagvall¹,

Christensson²

2016

Acta Derm Venerol

View full text Add to dashboard Cite

show abstract

“…14 Clarifying the nature of an exposure is further complicated by the variable nomenclature used in product labelling. 11 Over the period of this study, four different lavender allergen preparations were in use. The historical details of how this situation developed are unclear; however, the basic rationale was to broaden the testing to reflect the diverse forms of potential lavender exposure.…”

Section: Discussionmentioning

confidence: 99%

“…Formal studies examining the allergenicity of lavender oil in humans have produced variable results, and it has been suggested that this can be explained by the effect of autoxidation, leading to the generation of more potent contact allergens. 11 Both linalool and linalyl acetate are only weakly allergenic when present in their pure form; however, autoxidation leads to the production of potent sensitizers, in particular hydroperoxides. [15][16][17][18] It is thus advised that testing be performed with the oxidized forms of these chemicals.…”

Section: Discussionmentioning

confidence: 99%

“…Lavender oil is distilled from Lavandula angustifolia, spike lavender oil from Lavandula latifolia, and lavandin oil from cultivars of the hybrid Lavandula × intermedia. 11,12 In contrast, lavender absolute is manufactured from L. angustifolia flowers by a process involving hexane and ethanol extraction. 13 Although lavender absolute and the different types of lavender oil vary in their specific compositions, they share a common major constituent in linalool.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Contact allergy and allergic contact dermatitis caused by lavender: A retrospective study from an Australian clinic

et al. 2019

View full text Add to dashboard Cite

Results:Among the 2178 patients patch tested with lavender over this period, a total of 58 positive reactions were recorded in 49 individuals, giving a positive patch test prevalence for patients tested with lavender of 2.2%. Twenty-seven patients were diagnosed with ACD. The most common sources of exposure to lavender were personal care products and essential oils.Of the patients with ACD, 74% were tested with lavender absolute, with positive results in 90% of cases.Conclusion: Lavender is an uncommon cause of ACD but is important to consider, given the potential for exposure through the use of personal care items and essential oils.allergic contact dermatitis, essential oil, face eczema, hand dermatitis, hand eczema, lavender, patch test, sensitization

show abstract

“…Tanto o escore de intensidade de odor quanto o de aceitação do odor do OML foram maiores ao se comparar com os demais óleos avaliados (p<0,05), desta forma é possível que esta fragrância tenha obtido os maiores escores pelas suas notas olfativas serem consideradas como muito conhecidas popularmente, por sua constante aplicação em produtos cosméticos, de higiene pessoal, perfumaria, na terapia, tornando-a importante comercialmente (GANGEMI et al, 2015).…”

Section: Discussionunclassified

ANÁLISE DA COMPOSIÇÃO QUÍMICA E DE ACEITAÇÃO SENSORIAL DA FRAGRÂNCIA DA FLOR MASCULINA DO BURITIZEIRO (Mauritia flexuosa L.f.; Arecaceae)

Chicrala-Matos¹,

Maia²,

Gonçalves³

2017

Enci Bio

View full text Add to dashboard Cite

RESUMOO buritizeiro (Mauritia flexuosa) floresce quase o ano todo, sendo as flores subutilizadas e pouco exploradas comercialmente. Teve-se como objetivo analisar a composição química e a aceitação sensorial da fragrância da flor masculina do buritizeiro, pelo sexo feminino. Para análise química os voláteis florais captados pela técnica de headspace dinâmico foram submetidos a cromatografia gasosa acoplada à espectrometria de massa. À análise sensorial usou-se uma adaptação da técnica de headspace dinâmico, utilizando frasco Dreschel. A análise sensorial avaliou: intensidade, aceitação e aplicação do odor floral. À comparação entre avaliadores à intensidade e aceitação do odor, usou-se teste de Kruskal-Wallis, seguido pelo pós-teste de Dunn (p<0,05). Pelos resultados da composição química, houve prevalência, entre alcanos, do tridecano (81,3% a 86,6%) em todas as amostras avaliadas; identificou-se monoterpenos (α-pineno, β-mirceno, (Z)-β-ocimeno, (E)-β-ocimeno) e sesquiterpenos (9-epi-(E)-cariofileno, biciclogermacreno, pristano). Na análise sensorial do óleo mineral odorizado com a fragrância do buritizeiro (OMB), os julgadores atribuíram escore 1 -"muito fraco", quanto à intensidade do odor e, escore 3 -"não gostei nem desgostei" quanto à aceitação do odor. Quanto à aplicação do odor do OMB: 52% empregariam em produtos de higiene, limpeza e cosméticos, enquanto 48% não responderam ou não usariam em nenhum produto. Conclui-se que a técnica de headspace dinâmico foi eficaz à coleta dos voláteis florais de Mauritia flexuosa, a adaptação da técnica de headspace dinâmico foi adequada para odorizar o OMB e à aceitação pela população feminina do seu odor, a mesma mostrou-se indiferente. PALAVRAS-CHAVE: buriti, fragrância, headspace ANALYSIS OF THE CHEMICAL COMPOSITION AND SENSORY ACCEPTANCE OF THE MALE FLOWER FRAGRANCE OF MORICHE PALM (Mauritia

show abstract

Contact dermatitis as an adverse reaction to some topically used European herbal medicinal products – Part 2: Echinacea purpurea–Lavandula angustifolia

Cited by 20 publications

References 99 publications

Patch Testing with Main Sensitizers Does Not Detect All Cases of Contact Allergy to Oxidized Lavender Oil

Patch Testing with Main Sensitizers Does Not Detect All Cases of Contact Allergy to Oxidized Lavender Oil

Contact allergy and allergic contact dermatitis caused by lavender: A retrospective study from an Australian clinic

ANÁLISE DA COMPOSIÇÃO QUÍMICA E DE ACEITAÇÃO SENSORIAL DA FRAGRÂNCIA DA FLOR MASCULINA DO BURITIZEIRO (Mauritia flexuosa L.f.; Arecaceae)

Contact Info

Product

Resources

About