Contact allergy to octocrylene

Carrotte-Lefebvre, I.; Bonnevalle, A.; Ségard, M.; Delaporte, Éric; Thomas, Peter A.

doi:10.1034/j.1600-0536.2003.480108_2.x

Cited by 42 publications

(28 citation statements)

References 4 publications

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“…On the other hand, the irradiation was delivered in one acute dose, while in radiotherapy the treatment is given in fractionated doses. However, the lesions we observed were close to those observed during or after radiotherapy [10,[14][15][16] so we assume that this model could serve as a suitable experimental model for developing biomarkers for patients treated with radiotherapy.…”

Section: Spot Train Shifts In Pi After Irradiationmentioning

confidence: 95%

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Time‐course analysis of mouse serum proteome changes following exposure of the skin to ionizing radiation

et al. 2007

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Radiation-induced lesion outcomes of normal tissues are difficult to predict. In particular, radiotherapy or local exposure to a radioactive source by accident can trigger strong injury to the skin. The finding of biomarkers is of fundamental relevance for the prediction of lesion apparition and its evolution, and for the settlement of therapeutic strategies. In order to study radiationinduced cutaneous lesions, we developed a mouse model in which the dorsal skin was selectively exposed to ionizing radiation (IR). 2-D difference gel electrophoresis (2-D DIGE) coupled with MS was used to investigate proteins altered in expression and/or PTM in serum. Proteome changes were monitored from 1 day to 1 month postirradiation, at a dose of 40 Gy, in this specific model developing reproducible clinical symptoms ranging from erythema to skin ulceration with wound healing. About 60 proteins (including some isoforms and likely post-translational variants), representing 20 different proteins, that exhibited significant and reproducible kinetic expression changes, were identified using MS and database searches. Several proteins, down-or up-regulated from day one, could prove to be good candidates to prognosticate the evolution of a skin lesion such as necrosis. In addition, we observed shifts in pI of several spot trains, revealing potential PTM changes, which could also serve as indicators of irradiation or as predictors of lesion severity.

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Section: Spot Train Shifts In Pi After Irradiationmentioning

confidence: 95%

“…Recent radiation accidents [11,12] have highlighted the role of damage to the cutaneous system in the prognosis and outcome of radiation-induced multiorgan failure [13]. More commonly, a variety of numerous radiation-induced skin reactions are often observed in the course of or following radiation therapy [10,[14][15][16].…”

Section: Introductionmentioning

confidence: 99%

Time‐course analysis of mouse serum proteome changes following exposure of the skin to ionizing radiation

et al. 2007

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“…The first cases of PACD from octocrylene were reported in 2003 by CarrotteLefebvre et al, 6 and since then, only 4 cases have been reported in 2 other articles. 7,8 However, very recently, a study on photopatch testing in Italy reported 19 cases of positive photopatch test reactions to octocrylene.…”

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confidence: 99%

Octocrylene, an Emerging Photoallergen

Avenel-Audran

Dutartre²,

Goossens³

et al. 2010

Arch Dermatol

111

102

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Background: Octocrylene is a new emerging photoallergen. We report and discuss 50 cases of photoallergic contact dermatitis from octocrylene use and/or positive photopatch test reactions to this UV filter and draw attention to the unexpected association in adults with a history of photoallergic contact dermatitis from ketoprofen.Observations: Patients were divided in 3 groups: group A comprised 11 children; group B, 28 adults with a history of photoallergy from sunscreen products; and group C, 14 adults systematically tested with octocrylene because of a history of photoallergy from ketoprofen. All patients but 3 in group C had positive test reactions to octocrylene. Ten of 11 children in group A and 9 of 28 adults in group B had positive patch test reactions to octocrylene. One child in group A, the other 19 adults in group B, and 11 of 14 adults in group C had positive pho-

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“…Emerging photoallergens include drometrizole and Tinosorb M ® (28,84,(91)(92)(93)(94)(95). Tinosorb M, an efficient sunscreen using microfine particle technology, provides UV absorption by a photostable organic molecule as well as light scattering and light reflection by its microfine structure (96).…”

Section: Photoallergens Sunscreensmentioning

confidence: 99%

Photoallergy

Honari¹

2014

Reviews on Environmental Health

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Contact allergy to octocrylene

Cited by 42 publications

References 4 publications

Time‐course analysis of mouse serum proteome changes following exposure of the skin to ionizing radiation

Time‐course analysis of mouse serum proteome changes following exposure of the skin to ionizing radiation

Octocrylene, an Emerging Photoallergen

Photoallergy

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