Population dynamics models consisting of nonlinear difference equations allow us to get a better understanding of the processes involved in epidemiology. Usually, these mathematical models are studied under a deterministic approach.However, in order to take into account the uncertainties associated with the measurements of the model input parameters, a more realistic approach would be to consider these inputs as random variables. In this paper, we study the random time-discrete epidemiological models SIS, SIR, SIRS, and SEIR using a powerful unified approach based upon the so-called adaptive generalized polynomial chaos (gPC) technique. The solution to these random difference equations is a stochastic process in discrete time, which represents the number of susceptible, infected, recovered, etc individuals at each time step. We show, via numerical experiments, how adaptive gPC permits quantifying the uncertainty for the solution stochastic process of the aforementioned random time-discrete epidemiological model and obtaining accurate results at a cheap computational expense. We also highlight how adaptive gPC can be applied in practice, by means of an example using real data.
KEYWORDSadaptive gPC, computational methods for stochastic equations, computational uncertainty quantification, random nonlinear difference equations model, random population dynamics model, random time-discrete epidemiological model, stochastic difference equations
INTRODUCTIONDiscrete models, usually expressed via finite difference equations, and continuous models, often expressed by means of ordinary and partial differential equations, allow us to get a better understanding of the processes involved in epidemiology. 1-5 These models for population dynamics have been usually studied in a deterministic sense, treating the involved input parameters (initial conditions, forcing term, and/or coefficients) as constants. Recent examples in this regard, dealing with important epidemiological models by applying new deterministic approaches, like nonstandard finite difference schemes, modal infinite series expansions, analysis of bifurcations, for example, include previous works. [6][7][8] However, due to the inherent uncertainty associated with epidemiological phenomena, it would be better to treat the input parameters in a random sense. For instance, the coefficient that describes the proportion of individuals that recover from a disease and become susceptible again should take into account the uncertainties involved in the measurements, due to errors in the collection of data, missed individuals, lack of information, etc.The most well-known method to deal computationally with stochastic systems is Monte Carlo simulation. 9 Although it is an effective and easy to implement approach to quantify the uncertainty, the slowness to get accurately the digits in the computations makes this technique computationally expensive.Only recently, some random continuous-time epidemic models have been studied using generalized polynomial chaos (gPC). [10][11][12]...