Conservative management of a myxoid endometrial stromal sarcoma in a 16-year-old nulliparous woman

Prolonged long-term survival of low-grade endometrial stromal sarcoma patients with lung metastasis following treatment with medroxyprogesterone acetate

“…Although the behavior of LGESS is relatively indolent, late recurrences and distant metastases may occur [10]. The risk of recurrence is thought to be as high as 50%, although these tumors are usually slow growing and the recurrences occur late.…”

Myxoid Endometrial Stromal Sarcoma: A Case Report and Literature Review

“…They have suggested that myxoid ESS is similar to typical low grade ESS in recurrence and survival time [6,14]. However, our case provides a different view about this disease.…”

“…Previous two case reports of myxoid ESS noted that there was no evidence of recurrence after surgery within 21 months. One was treated adjuvant chemotherapy with Adriamycin and dacarbazine [6], while the other was a 16-year old woman who underwent mass excision of uterus and adjuvant progestin therapy [14]. Second, 13 months after the diagnosis, the myxoid ESS of low grade type in the present case was transitioned into high grade sarcoma.…”

Successful pregnancy after fertility-preserving surgery for endometrial stromal sarcoma

“…The evaluation of the margin must be required for diagnosis. Stadsvold JL et al (2) present a case of low-grade myxoid ESS in a 16-year-old nulliparous adolescent female managed by local resection and uterine reconstruction, but whether the patient they reported had conceived successfully was not reported. The fact that her uterus was left intact to preserve fertility gives reason to believe that conservative surgery might enable the potential for future fertility and might be feasible.…”

“…Generally, ESS occurs in perimenopausal women, with most women ranging 42-53 years of age (2). The initial treatment is mainly surgical and generally involves total hysterectomy with adnexectomy.…”