Epithelial ovarian carcinoma is a high mortality neoplasm in gynecologic malignancy. It usually can metastasize to distant organs such as pleura, liver, lung, and lymph nodes. However, the skin metastases are not common and related to very poor prognosis. Here we report a 54-year-old patient with ovarian clear cell carcinoma with skin metastases on the anterior chest at 11 months after initial diagnosis. Although she received palliative chemotherapy, she expired due to disease progression 2 months later after the diagnosis of skin metastases.
Myxoid type of endometrial stromal sarcoma (ESS) is a very rare tumor of uterine malignancies. Although several cases about pathologic features for the diagnosis of ESS have been reported, it remains still difficult to find a study of the clinical course, management, and outcome of ESS. Here we report a postmenopausal woman with myxoid ESS of low grade type who had aggressive clinical features. Although adequate progestin therapy was provided followed by total abdominal hysterectomy and bilateral salpingo-oophorectomy, they failed to prevent early recurrence of ESS. Following cytoreductive surgery and chemotherapy were also proved to be refractory to control the rapid progression of ESS.
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