Successful pregnancy after fertility-preserving surgery for endometrial stromal sarcoma

Reproductive outcome after uterine-sparing surgery for endometrial stromal sarcoma

“…In conclusion, we found few literature cases (13) of pregnancy after leiomyosarcoma diagnosis (Salman et al, 2007), and only one case of pregnancy after UESS (Yan et al, 2010). Our case is the second to be described in cases of ESS after the case reported in (Delaney et al, 2012 Aug).…”

“…There are no clinical guidelines for young patients who desire to preserve fertility, and we found only two cases of gestation after UESS (Yan et al, 2010) or ESS (Delaney et al, 2012 Aug). In these cases, conservative surgery is possible.…”

“…In these cases, conservative surgery is possible. This surgery is later completed with another operation to increase the margins (Yan et al, 2010) and wait for spontaneous pregnancy (Yan et al, 2010;Delaney et al, 2012 Aug) or proceed with in vitro fertilization as in our patient (this was done for the purpose of achieving pregnancy as soon as possible and to complete the surgery afterwards).…”

“…It has been suggested that the treatment should last 5 years (and be life-long for others) because the recurrence rate is 50% at 36 to 68 months or even years later and is not affected by adjuvant chemotherapy or radiation therapy. We treated our patient with megestrol acetate 160 mg/d and without chemotherapy, whereas the authors of (Yan et al, 2010) use 20 mg/d and adjunctive chemotherapy (etoposide and cisplatin). Because the tumor is hormone-dependent, hormone replacement therapy and tamoxifen are contraindicated in premenopausal patients.…”

Successful Pregnancy with Endometrial Stromal Sarcoma (ESS)

“…ESS can be mistaken for leiomyoma because clinical presentation mimics each other and often needs HPE to establish correct diagnosis [2,3]. In this article, we report a case of ESS in a young unmarried female of 23 years, which was misdiagnosed as leiomyoma, but the patient was able to conceive and deliver a healthy baby after debulking surgery to remove myoma was mistakenly done.…”