Congenital Mitral Valve Regurgitation in Adult Patients

Abstract

Congenital MVR is rare and often misdiagnosed in adults. Mitral valve repair is feasible in the majority of patients, with excellent immediate and medium-term results.

Outcomes and Prognostic Factors for Adult Patients With Congenital Heart Disease Undergoing Primary or Reoperative Systemic Atrioventricular Valve Surgery

“…Forty-two patients had repairs of the mitral valve and six had replacements. 2 There was one death in the study from ventricular fibrillation, and 24% had mild regurgitation at last follow-up. In a study by Zegdi et al, 3 15 patients greater than 16 years of age were studied (median age 38 years).…”

“…Two prior studies have looked at adults with congenital mitral valve disease undergoing surgery. In a study by Jiang et al, 2 48 patients with a median age of 42 years underwent surgical intervention. Forty-two patients had repairs of the mitral valve and six had replacements.…”

“…Previous study of valvular surgery in ACHD is limited, largely consisting of case series. For instance, two prior studies have examined adults with congenital mitral valve disease undergoing surgery, 2,3 and while several studies have examined patients with ccTGA requiring surgical intervention, [4][5][6][7][8][9] only two of these studies have analyzed risk factors for adverse outcomes. 6,9 The AVSD studies largely concentrate on the pediatric population undergoing primary repair.…”

Perioperative Care of Adults with Congenital Heart Disease for Non-cardiac Surgery

“…Adult patients with a bicuspid aortic valve are more likely to have premature coronary artery disease and aortic calcification or stenosis. A combination of turbulent flow and genetic alterations in tissue matrix can lead to aortic dilation [22,23]. Aortic root dilation predisposes patients to aortic insufficiency, while dilation of ascending aorta increases the risk of aortic dissection.…”