Comprehensive Review of Keloid Formation

Shaheen, Abeer

doi:10.15226/2378-1726/4/5/00168

Cited by 13 publications

(45 citation statements)

References 42 publications

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“…Other promoting factors include the type of injury, melanin pigmentation, anatomical site, age of onset, and gender. [ 3 ]…”

Section: Discussionmentioning

confidence: 99%

“…[ 1 ] Although keloids are benign lesions with no malignant potential,[ 2 ] it can significantly degrade the patient's physical and psychological quality of life, especially if there is excessive scarring. [ 3 ] The initiation may occur from minor injuries such as insect bite, acne, lacerations, tattoos, vaccinations, injections, skin piercing or from major wounds such as surgical incisions, burn wounds, or abrasions. [ 2 ]…”

Section: Introductionmentioning

confidence: 99%

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A Case of Keloid

Vannala

Mahabob

Radhakrishnan³

et al. 2021

Journal of Pharmacy and Bioallied Sciences

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Keloids are unorganized proliferation of fibrous tissue, usually arising from a site of injury, due to an aberrant healing process. Clinically, it presents as an ugly scar tissue on the skin and shows genetic predilection. They cause esthetic, physical, and psychological disturbances in the affected individuals. Such patients require special precautions during the normal surgical procedures. Keloid treatment is prone to a high degree of resistance and recurrence. In this article, one such a case is reported along with a review of the literature discussing the nature of the lesion, treatment options, and the recommended precautions.

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“…Other promoting factors include the type of injury, melanin pigmentation, anatomical site, age of onset, and gender. [ 3 ]…”

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

A Case of Keloid

Vannala

Mahabob

Radhakrishnan³

et al. 2021

Journal of Pharmacy and Bioallied Sciences

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“…Keloidde oluşan nedbe dokusu yara sınırları içinde kalmayıp çevreye yayılır. Keloidin kanserden farkı, kanser dokusunda hücre sayısı artış gösterirken keloidde bağ dokusu artışı olmasıdır (47).…”

Section: Hipertrofik Skar Ve Keloidunclassified

Wound Repair and Experimental Wound Models

Baktir¹

2020

Experimed

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“…It is characterized by a wide, slightly soft, and shiny surface lump and disrupting the appearance. The exact mechanism for its occurrence has not been fully resolved, although several theories have explained its causes [1], [2], [3].…”

Section: Introductionmentioning

confidence: 99%

“…Melanin is a natural pigment in human and animal skin. It has different types of colors, and it is an indicator determining human skin color [2], [7]. The measurements of melanin or skin color concentration can be done using a spectrophotometer or colorimeter, also known as a chromameter, and the type to be used must be in accordance with the Commission International d'Eclairage (CIE) laboratory standards.…”

Section: Introductionmentioning

confidence: 99%

Correlation of Melanin Content with Collagen Density in Keloid Patients

Wihastyoko

Perdanakusuma

Soeharto

et al. 2021

Open Access Maced J Med Sci

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BACKGROUND: Keloid is a form of wound healing that results from fibrous tissue activity. It can develop beyond the boundaries of the original wound, extends into the dermis layer, and disrupting the appearance. Previously, no studies have revealed a correlation between melanin pigment and keloid. AIM: This research aimed to describe the correlation between melanin concentration and collagen deposition in keloid tissue. MATERIALS AND METHODS: A prospective study conducted through the application of a cross-sectional analytic survey method. The color of the skin was measured using a chromameter, and a histopathologic examination was performed on the skin surrounding the keloid, as well as the keloid tissue. Data were analyzed using a t-test, correlation, and linear regression statistics. RESULTS: The results showed a significant difference between melanin concentration and collagen deposition in the skin surrounding the keloid tissue. No significant difference was observed between melanin concentration in the surrounding skin of keloid and those in the keloid tissue, as well as collagen deposition. Meanwhile, the melanin concentration in the surrounding skin of keloid and keloid tissue had a significant relationship with fibrocytes number. CONCLUSION: There is a significant correlation between melanin concentrations and collagen density in the keloid tissue.

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Comprehensive Review of Keloid Formation

Cited by 13 publications

References 42 publications

A Case of Keloid

A Case of Keloid

Wound Repair and Experimental Wound Models

Correlation of Melanin Content with Collagen Density in Keloid Patients

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