Composition and Chemical Variability of Root Bark oil from Ivoirian <i>Cleistopholis patens</i>

Ouattara, Zana Adama; Yapi, Thierry Acafou; Békro, Yves-Alain; Mamyrbékova-Békro, Akhanovna J.; Paoli, Mathieu; Tomi, Pierre; Casanova, Joseph; Bighelli, Ange; Tomi, Félix

doi:10.1177/1934578x1801300630

Cited by 3 publications

(2 citation statements)

References 19 publications

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“…The analysis revealed predominantly essential oils, fatty acids, esters and terpenoids. Ouattara et al, (2018) in their work isolated several essential oils in the stem bark extract of C.patens including patchoulenone, βpinene, bornyl acetate, α-pinene, juvenile hormone III, and β-elemol among others. Several essential oils have been used as therapeutic agents since ancient times, and some of them have been scientifically proven to possess medicinal properties, including anti-inflammatory (Koudou et al, 2005), antiviral (Loizzoa et al, 2007), antitumor (M'Barek, 2007), cytotoxic (Zarai et al, 2011) and antimicrobial activities (Alviano et al, 2007).…”

Section: Discussionmentioning

confidence: 99%

Antibacterial activity, phytochemicals and essential oils in ethyl acetate extract of Cleistopholis patens

Daniels¹,

Temikotan²,

Fadairo³

2020

Int. J. Curr. Res. Biosci. Plant Biol.

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The ethyl acetate extract of Cleistopholis patens was investigated for its antibacterial activity against ten bacterial strains and compared with standard antibiotics. The extract was purified and antibacterial activities were compared with the crude extract. The multiple antibiotic resistant (MAR) index was determined using known method. The phytochemical components were examined and the essential oil components were also investigated using the GC-MS spectra analysis. The antibacterial test revealed the plant to be active against the test organisms. However, the crude extract showed larger zones of inhibition compared to the purified extract. The multiple antibiotic resistance (MAR) index ranged between 0.42 and 1.0. The phytochemical analysis revealed the presence of glycosides, steroids, phenols and tannin. Mineral content of plants are Na (24.03%), K (30.14%), Ca (32.31%), Mg (26.09%), Zn (28.09%), Fe (6.70%) and Cu (0.03%). The GC-MS analysis showed the presence of essential oils predominantly fatty acids, sterols, esters, terpenes and alcohols with fatty acid occurring in abundance. The presence of essential oil in this plant could be responsible for its biological activities and the result of this work supports the use of the plant in the traditional medicine and herbal treatment of diseases.

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Section: Discussionmentioning

confidence: 99%

Antibacterial activity, phytochemicals and essential oils in ethyl acetate extract of Cleistopholis patens

Daniels¹,

Temikotan²,

Fadairo³

2020

Int. J. Curr. Res. Biosci. Plant Biol.

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“…The root bark of C. Patens essential oil was shown by Watermann and Mohammad (1985) in their work to contain two sesquiterpenes and five alkaloids. Quattara [25] however discovered various sesquiterpenes in C. patens. The biological activities of isolated sesquiterpenes that include: α-pinene and (+)-β-pinene found in C. patens were found to possess antifungal activities against Candida albicans [26] and antiinflammatory effects in human chondrocytes exhibiting potential antiosteoarthritic activity [27].…”

Section: Compounds Identified In Fraction Cp12 3 Of C Patensmentioning

confidence: 99%

Characterization of Sesquiterpenes and Antibacterial Activities of Extracts from Piliostigma reticulatum (DL.) Hochst and Cleistopholis patens (Benth.) Engl & Diels against Shigella dysenteriae and Streptococcus pyogenes

Daniels

Owoyemi

Famurewa

et al. 2019

MRJI

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Aim: The study characterized sesquiterpenes from the bark extracts of Piliostigma reticulatum and Cleistopholis patens and subsequently tested the extracts for their antibacterial activities. Methodology: Ground stem barks of P. reticulatum and C. patens were obtained and extracted with ethyl acetate. The extract from both plants were screened for antibacterial activities against Shigella dysenteriae and Streptococcus pyogenes using the agar well diffusion method. Furthermore, fractions obtained from the crude extracts were also assayed for antibacterial efficacy using the disc diffusion method. The phyto-constituents of the extracts were identified using Gas chromatography and mass spectra (GC-MS) and subsequent characterization was achieved via Nuclear Magnetic Resonance Spectroscopy (NMR). Results: The results showed that P. reticulatum extract had more antibacterial activities on S. dysenteriae with zones of inhibition ranging from 6 mm – 14 mm while it had lesser inhibitory effect against S. pyogenes with zones of inhibition of 10 mm and 8 mm at concentrations of 100 mg/mL and 80 mg/mL respectively. However, C. patens was effective against S. pyogenes with zones of inhibition of 18 mm, 16 mm, 14 mm, 13 mm, and 8 mm at concentrations of 100, 60, 40, 20 and 10 mg/mL respectively. Crude extracts from both plants exhibited higher antibacterial activity compared to purified fractions against test organisms. A number of five (5) Sesquiterpenes (azulenes, alpha and beta pinene, Germacrene D, Limonene, and Farnesol) were identified from the extracts of both plants. Conclusion: The presence of sesquiterpenes in P. reticulatum and C. patens could be responsible for the antibacterial activities on the test organisms (S. dysenteriae and S. pyogenes) evaluated in this study and subsequently justify their use in folkloric medicine. Hence, the extracts obtained from P. reticulatum and C. patens could be considered as a potential and rich source of antibacterial agent to control infections posed by the test organisms (S. dysenteriae and S. pyogenes).

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Ethnopharmacological survey of aromatic medicinal plants used in the treatment of the most recurrent diseases in the locality of Oyem, Gabon

Obiang

Misso

Mba

et al. 2023

ADV TRADIT MED (ADTM)

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Composition and Chemical Variability of Root Bark oil from Ivoirian Cleistopholis patens

Cited by 3 publications

References 19 publications

Antibacterial activity, phytochemicals and essential oils in ethyl acetate extract of Cleistopholis patens

Antibacterial activity, phytochemicals and essential oils in ethyl acetate extract of Cleistopholis patens

Characterization of Sesquiterpenes and Antibacterial Activities of Extracts from Piliostigma reticulatum (DL.) Hochst and Cleistopholis patens (Benth.) Engl & Diels against Shigella dysenteriae and Streptococcus pyogenes

Ethnopharmacological survey of aromatic medicinal plants used in the treatment of the most recurrent diseases in the locality of Oyem, Gabon

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