Composition and antimicrobial activity of the essential oil of Clinopodium ascendens (Jordan) Sampaio from Madeira

Abstract

1 H-and 13 C-NMR. The oil was dominated by C 3 oxygenated p-menthane derivatives: cis-isopulegone (75.2%), pulegone (6.9%), neoiso-isopulegol (6.0%) and trans-isopulegone (4.5%). The whole essential oil was tested against a variety of bacteria, both Gram-positive and Gram-negative, and two fungi; it exhibited remarkable activity against Escherichia coli and was active against Agrobacterium tumefasciens and Staphylococcus aureus and the phytopathogenic fungus Botrytis cinerea. It was ineffective against Streptococcus faecium, Streptococcus mutans and Candida albicans.

Volatiles and seasonal variation of the essential oil composition from the leaves of Clinopodium macrostemum var. laevigatum and its biological activities

“…glycinea and E. coli strain DH5␣ (Table 4). The essential oil of Clinopodium ascendens containing high levels of pmenthane compounds, showed its ability to inhibit the growth of E. coli strain CCMI 270 and A. tumefaciens (Castilho et al, 2007). Similar results were found by the essential oil of Mentha rotundifolia for E. coli (Riahi et al, 2013).…”

Depressant effects of Clinopodium mexicanum Benth. Govaerts (Lamiaceae) on the central nervous system

“…In the USA, a decoction of Clinopodium douglasii has been used by the Costanoan Indians as an anthelmintic remedy (Bocek, 1984). In Portugal, the leaves of Clinopodium ascendens are used as a mouth freshener and to alleviate headache and toothache (Castilho et al, 2006).…”

Thuja occidentalis: identification of volatiles and electroantennographic response by the invasive cedar bark beetle, Phloeosinus aubei

“…Structural assignments of the obtained diastereomers followed Castilho et al. () and Moreira and Corrêa () (Organikum, , p441). pure enantiomers of sulcatol by reaction of the enantiomers of methyloxirane (Sigma‐Aldrich) with the Grignard reagent of 1‐chloro‐3‐methyl‐2‐butene (Sigma‐Aldrich), according to standard laboratory procedures (Organikum, , p576). (+)‐sabina ketone by ozonolysis of (–)‐sabinene (isolated from China white camphor oil – courtesy of P. Kaders, Hamburg, Germany), as described by Schmidt (). (–)‐ cis ‐thujanol ( cis ‐sabinene hydrate) by reaction of (+)‐sabina ketone with methyl magnesium bromide according to Wallach (). (–)‐terpinen‐4‐ol by acid catalysed hydroxylation and rearrangement of (–)‐sabinene.…”