Composite cerebral metastasis and oligodendroglioma: an exceptional form of mixed neoplasia

Abstract

Our report describes the uncommon case of a 61 year old female patient who underwent a left parietooccipital craniotomy and extirpation of a malignant tumor. Histological examination revealed a metastatic carcinoma of mammary origin intimately intermingled with a calcified oligodendroglioma WHO II. The preexisting oligodendroglial part had been detected four years before, but since then had been misinterpreted as a glious scar resulting from a previous brain trauma. Three years before neurosurgical intervention, the patient had undergone a left side mastectomy. The histological finding at that time was a solid breast tumor WHO T1N0. The occurrence of cerebral mixed neoplasias and possible causal factors are discussed.

Simultaneous occurrence of cerebellar medulloblastoma and pituitary adenoma: A case report

“…Interestingly, Gironimi et al in 1981 reported the case of a primary Burkitt-type lymphoma of the CNS, developed in an 11-year-old boy 6 months after extirpation of an astrocytoma, stressing the notion of collision tumors and their differential diagnosis [ 6 ]. Other researchers, additionally, have been described the coexistence of oligodendroglioma with anaplastic astrocytoma [ 9 ], pleomorphic xanthoastrocytoma [ 7 ], metastatic breast carcinoma [ 10 ] and juvenile pilocytic astrocytoma [ 11 ], within CNS.…”