1993
DOI: 10.1590/s0102-76381993000200004
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Comportamento da função do ventrículo esquerdo a longo prazo no transplante cardíaco ortotópico

Abstract: A ciclosporina-A introduziu mudanças nos protocolos de seguimento pós-operatório, considerando-se a maior estabilidade hemodinâmica dos paOs resultados dos estudos referentes à função do coração e ao comportamento do sistema circulatório são motivo de controvérsias 16 . Os trabalhos, em sua maioria, relatam que a função contrátil do coração desnervado mantém-se inalterada a longo prazo 2, 10 , 12; contudo, outros demonstram haver redução importante da função ventricular 14

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Cited by 4 publications
(5 citation statements)
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References 12 publications
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“…Valvular involvement presents progressive aspect over time, affecting about 7.8% of the patients in the fifth year after transplantation and occurring in 14.2% by the tenth year [2,4,6]. Similar outcomes were observed in InCor's research, and were presented in a previous publication [18]. The absence of uniformity in the tricuspid insufficiency quantification and the varied distribution of factors that contribute to its evolution are responsible for the occurrence of the dispersed values.…”
Section: Resultssupporting
confidence: 77%
“…Valvular involvement presents progressive aspect over time, affecting about 7.8% of the patients in the fifth year after transplantation and occurring in 14.2% by the tenth year [2,4,6]. Similar outcomes were observed in InCor's research, and were presented in a previous publication [18]. The absence of uniformity in the tricuspid insufficiency quantification and the varied distribution of factors that contribute to its evolution are responsible for the occurrence of the dispersed values.…”
Section: Resultssupporting
confidence: 77%
“…The importance of this entity can be observed in the comparative analysis of the survival curves presented by the International Society for Heart and Lung Transplantation, in which patients who developed vasculopathy had a higher mortality rate than the others. 13 The graft vascular disease is responsible for 17% of the deaths and can be detected as early as the first year after transplantation, reaching in the third year figures in the order of 42% by cinecoronariography and 75% by intravascular ultrasonography [13][14][15][16][17].…”
Section: Graft Vascular Diseasementioning
confidence: 99%
“…The clinical diagnosis of graft vascular disease is difficult, since myocardial ischemia presents a silent course because it is a denervated heart. In the advanced stage, the disease often manifests with signs of heart failure, arrhythmias or even sudden death [14,21,[30][31][32].…”
Section: Graft Vascular Diseasementioning
confidence: 99%
“…Na nossa série, os resultados têm mostrado que a incidência dessa complicação ocorre no primeiro ano de evolução em 13,6% dos pacientes, aumentando progressivamente até a 44,4% no quinto ano 2,15 . Esses dados são comparáveis aos reportados na literatura e a introdução da ciclosporina-A na imunossupressão não parece ter modificado a sua incidência.…”
Section: Evolução Clínca Após O Transplanteunclassified