2016
DOI: 10.4103/0972-124x.194269
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Comparison the efficacy of herbal mouthwash with chlorhexidine on gingival index of intubated patients in Intensive Care Unit

Abstract: Background:Intubated patients in Intensive Care Unit (ICU) are not able to take care of their mouth health, so they are at risk of bacterial colonization and dental plaques formation that can lead to systemic diseases such as pneumonia and gingivitis.Aims:In randomized, double-blind clinical study, the efficacy of natural herbal mouthwash containing Salvadora persica ethanol extract and Aloe vera gel was compared with chlorhexidine on gingival index (GI) of intubated patients in ICU.Materials and Methods:Seven… Show more

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Cited by 32 publications
(23 citation statements)
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“…The use of chlorhexidine gluconate solution, which is a gold standard antiseptic agent, is indeed proven to have high antibacterial, antiviral and antifungal activity with a broad spectrum (Depaola & Spolarich, 2007;Nicolosi et al, 2014). Although the use of chlorhexidine has been proven to be safe, but it has side effects of mucosal irritation and desquamation and causes dry mouth (Azimi et al, 2016;Nicolosi et al, 2014;Potting et al, 2006;Rezaei et al, 2016). This is in line with this study which showed that there was a worsening of the oral mucosa of patients with ETT which was signed by worsening humidity in the lips, gingiva and mucosa subscales.…”
Section: Discussionmentioning
confidence: 99%
“…The use of chlorhexidine gluconate solution, which is a gold standard antiseptic agent, is indeed proven to have high antibacterial, antiviral and antifungal activity with a broad spectrum (Depaola & Spolarich, 2007;Nicolosi et al, 2014). Although the use of chlorhexidine has been proven to be safe, but it has side effects of mucosal irritation and desquamation and causes dry mouth (Azimi et al, 2016;Nicolosi et al, 2014;Potting et al, 2006;Rezaei et al, 2016). This is in line with this study which showed that there was a worsening of the oral mucosa of patients with ETT which was signed by worsening humidity in the lips, gingiva and mucosa subscales.…”
Section: Discussionmentioning
confidence: 99%
“…Given the anti-inflammatory and anti-oxidant properties of SP, its extracts can have an important role in preventing the onset and progression of periodontal disease, as stated in the current study. The majority of the studies discussed in this study observed the clinical therapeutic effect of SP on gingival or periodontal inflammation and health in terms of gingival status and plaque accumulation ( Table 4 ) [ 3 , 75 , 76 , 77 , 78 , 79 , 80 , 81 , 82 , 83 , 84 , 85 , 86 ]. In these inquiries, SP was introduced in the form of mouthwashes [ 75 , 77 , 78 , 79 , 81 , 82 , 83 ], toothpastes/dentifrices [ 80 , 85 , 86 ], chewing/brushing sticks [ 3 , 76 , 84 , 87 ] or periodontal films [ 88 ].…”
Section: Modes Of Action Of Salvadora Persica As Potential Adjuncts During Periodontal Therapy and In Periodontitis-asmentioning
confidence: 99%
“…The majority of the studies discussed in this study observed the clinical therapeutic effect of SP on gingival or periodontal inflammation and health in terms of gingival status and plaque accumulation ( Table 4 ) [ 3 , 75 , 76 , 77 , 78 , 79 , 80 , 81 , 82 , 83 , 84 , 85 , 86 ]. In these inquiries, SP was introduced in the form of mouthwashes [ 75 , 77 , 78 , 79 , 81 , 82 , 83 ], toothpastes/dentifrices [ 80 , 85 , 86 ], chewing/brushing sticks [ 3 , 76 , 84 , 87 ] or periodontal films [ 88 ]. Moreover, SP was applied in several concentrations as a pure SP product [ 3 , 76 , 78 , 80 , 84 , 86 , 87 ] or in combination with other herbal elements [ 75 , 77 , 79 , 81 , 82 , 83 , 85 ].…”
Section: Modes Of Action Of Salvadora Persica As Potential Adjuncts During Periodontal Therapy and In Periodontitis-asmentioning
confidence: 99%
“…The GI was scored and calculated according to Loe and Sillness. [ 6 7 8 ] The overall average gave the final GI score.…”
Section: Ethodologymentioning
confidence: 99%