Comparative evaluation of antiplaque efficacy between essential oils with alcohol-based and chlorhexidine with nonalcohol-based mouthrinses

Kulkarni, Prasad; Singh, Dhirendra Kumar; Jalaluddin, Mohammad; Mandal, Arnab

doi:10.4103/jispcd.jispcd_131_17

Cited by 10 publications

(8 citation statements)

References 19 publications

(19 reference statements)

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“…However, in the present study, the individuals in the periodontitis group underwent full-mouth scaling plus CHX, as described by Quirynen et al 25 , instead of EO. Despite some undesirable side effects due to its higher anti-plaque effectiveness, CHX is the first option for the short-term chemical dental biofilm control of periodontitis 14,[26][27][28][29] . Thus, whether a longer period of time is needed to observe the total protein level reduction in the presence of periodontitis is a subject for further studies, especially when considering the improvements in the classical clinical parameters.…”

Section: Discussionmentioning

confidence: 99%

“…Moreover, this group received oral hygiene instructions and rinsed with an EO mouthwash, which, according to Raslan et al 13 , provided additional benefits when compared to isolated mechanical procedures. Studies that have compared EOs with CHX demonstrated that EOs are a viable option for gingivitis patients due to their appropriate clinical benefits with less side effects 14,[26][27][28][29] . The present gingivitis patients showed statistically significant improvements at 3 months, as revealed by the PD, PI, and GI reductions.…”

Section: Discussionmentioning

confidence: 99%

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Salivary arginase activity after mechanical-chemical therapy

Castro

Cortelli

Rodrigues

et al. 2018

Rev. odontol. UNESP

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ResumoIntrodução: Componentes salivares podem ser usados como biomarcadores para diagnóstico e monitoramento de doenças orais. Há evidências de que um potencial biomarcador, arginase, está associado com os processos inflamatórios da doença periodontal, e após o tratamento sua atividade enzimática é reduzida em concordância com a melhora nos parâmetros clínicos. Objetivo: O presente estudo objetivou avaliar a atividade da arginase salivar em pacientes com gengivite e periodontite tratados com procedimentos mecânicos em estágio único combinados ao uso coadjuvante de enxaguatórios com óleos essenciais ou clorexidina, respectivamente. Material e método: Vinte e seis pacientes com gengivite e 16 pacientes com periodontite receberam exame periodontal completo antes e 3 meses após a terapia, em que mensurações de profundidade de sondagem, perda de inserção clínica, índice de placa e índice gengival foram realizadas. Nestas mesmas consultas os níveis de proteína total e a atividade de arginase salivar foram estabelecidos via espectrofotometria. Resultado: Todos os parâmetros clínicos melhoraram, em ambos os grupos, do exame inicial para o de 3 meses (p < 0,05). Adicionalmente, após tratamento para gengivite houve redução da atividade de arginase salivar e do nível de proteína total. Conclusão: Semelhante aos resultados clínicos, ambos os protocolos terapêuticos afetaram positivamente a atividade da arginase salivar; entretanto, estudos futuros são necessários para clarificar seu potencial como biomarcador salivar para o monitoramento periodontal. AbstractIntroduction: Salivary components can be used as biomarkers for diagnosing and monitoring oral diseases. There is evidence that one potential biomarker, arginase, is associated with the inflammatory processes of periodontal disease, and its enzymatic activity is reduced according to the improvement in the clinical parameters after treatment. Objective: The present study aimed to evaluate the salivary arginase activity in gingivitis and periodontitis patients treated with full-mouth mechanical procedures combined with the adjunctive use of essential oils or chlorhexidine mouthwash, respectively. Material and method: Twenty-six gingivitis and 16 periodontitis patients received complete periodontal examinations at the baseline and 3 months after therapy, in which the periodontal probing depth, clinical attachment loss, plaque index, and gingival index measurements were taken. At these same appointments, the salivary total protein level and salivary arginase activity were also established via spectrophotometry. Result: There were improvements in all of the clinical parameters (p < 0.05) evaluated from the baseline to 3 months in both groups. In addition, the salivary arginase activity and total protein levels were reduced after the gingivitis treatment. Conclusion: Similar to the clinical results, both therapeutic protocols positively affected the salivary arginase activity; however, further studies are necessary to clarify its potential as a salivary biomarker for periodont...

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Salivary arginase activity after mechanical-chemical therapy

Castro

Cortelli

Rodrigues

et al. 2018

Rev. odontol. UNESP

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“…The present study comprised 200 dental students 18–22 years of age, with gingival index of Score II (According to Loe and Silness (1963));[ 6 ] were randomly divided into two groups of 100 each ( n = 100). The first group was advised to rinse with 15 ml 0.12% chlorhexidine (CHX) mouthwash, and the second group with 15 ml of formulated herbal mouthwash twice daily for 30 s for 15 days along with their regular tooth brushing with a standard toothbrush and paste with no other restrictions in par with real-life situation.…”

Section: Aterials and M Ethodsmentioning

confidence: 99%

“…Naturally available herbs such as tulsi, triphala, neem, honey, ajwain, turmeric, etc., have been commonly used either alone or in combination as safe and effective antibacterial agents. [ 6 ]…”

Section: Introductionmentioning

confidence: 99%

A novel herbal formulation versus chlorhexidine mouthwash in efficacy against oral microflora

Vinod¹,

Sunil²,

Sethi³

et al. 2018

J Int Soc Prevent Communit Dent

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Aims and Objectives:The aim of the study was to compare and to analyze the antimicrobial efficacy of 0.12% chlorhexidine and new formulated herbal mouthwash after using for 14 days. The objective was to signify whether the noval herbal combination could be a better alternative mouthwash to Chlorhexidine (CHX).Materials and Methods:This is a double-blinded, random controlled research study conducted in the Department of Oral Pathology and Microbiology. A total of 200 dental students were selected randomly, comprising of two groups, 100 in each, aged between 18 and 22 years with gingival index of score II. The first group was advised to oral rinse with 0.12% chlorhexidine mouthwash and the second group with new formulated herbal mouthwash for 14 days. Saliva samples were collected on the day 0 (baseline), followed by day 7 and 14 and microbial colony count was performed. The data obtained was statistically analyzed using SPSS version 16. Student's t-test was applied for comparison of the mean microbial count between the two groups. Repeated measures analysis of variance followed by Tukey's post hoc test was applied to assess the changes from day 0 to day 7 to day 14. The statistical significance level was set at P < 0.05.Results:Microbial colonies were reduced better in chlorhexidine group on the day 7 whereas, on day 14, greater reduction was observed in the herbal group in both gender groups with high statistical significance (P < 0.001).Conclusions:Herbal mouthwash formulation performed effectively well on long-term usage, could be used as an alternative mouthwash to overcome the disadvantages of chlorhexidine.

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“…Essential oils have been used in the oral cavity for decades, with excellent results as agents that aid mechanical control (Haas et al, 2016). Most are used in mouthwash solutions (Kulkarni, Singh, Jalaluddin, & Mandal, 2017;Thomas, Thakur, & Mhambrey, 2015). However, coadjuvant chemical control has also been used in other forms such as dentifrices and subgingivally positioned slow-release devices (Ower, Ciantar, Newman, Wilson, & Bulman, 1995;Pessan, Al-Ibrahim, Buzalaf, & Toumba, 2008).…”

Section: ? (To All Analyses)mentioning

confidence: 99%

Antimicrobial activity of copaiba oil (Copaifera ssp.) on oral pathogens: Systematic review

Diefenbach

Muniz

Oballe

et al. 2017

Phytotherapy Research

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Copaifera ssp. produces an oil-resin that presents antiinflammatory, antitumor, antiseptic, germicidal, antifungal, and antibacterial activity. This systematic review aimed to analyze the antimicrobial action of Copaiba oil against oral pathogens, when compared to that of control substances. A search on Medline/PubMed, LILACS, SciELO, EMBASE, and SCOPUS databases were performed up to March 2017. To be included, the studies needed to perform any antimicrobial activity essay, using copaiba oil and a control substance. The antimicrobial effect of each substance, in each study, was extracted. Eleven studies were included, and several copaiba species were used. All studies showed that copaiba oil, regardless of its species, presented a bactericidal and/or bacteriostatic effect in in vitro analyzes. Only one study showed that the antimicrobial effect of the Copaifera officinalis was similar to the one found in chlorhexidine. A higher risk of bias was detected in most of the included studies. The studies demonstrated that the antimicrobial activity of copaiba oil, in most cases, is lower than chlorhexidine, which is considered the gold standard. However, there is great potential against oral bacteria. Further high quality studies are warranted in order to assess the efficacy of copaiba oil on oral pathogens.

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Comparative evaluation of antiplaque efficacy between essential oils with alcohol-based and chlorhexidine with nonalcohol-based mouthrinses

Cited by 10 publications

References 19 publications

Salivary arginase activity after mechanical-chemical therapy

Salivary arginase activity after mechanical-chemical therapy

A novel herbal formulation versus chlorhexidine mouthwash in efficacy against oral microflora

Antimicrobial activity of copaiba oil (Copaifera ssp.) on oral pathogens: Systematic review

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