2010
DOI: 10.3109/09546631003762639
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Comparison of therapeutic effects of oral doxycycline and azithromycin in patients with moderate acne vulgaris: What is the role of age?

Abstract: Azithromycin is at least as effective as doxycycline in the treatment of moderate acne vulgaris; however, in patients older than 18 years doxycycline is better.

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Cited by 39 publications
(24 citation statements)
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“…Until the late 1970s, P. acnes was susceptible to different antimicrobials including clindamycin, erythromycin and cyclines 5 . The safe and effective use of azithromycin for treatment of moderate acne vulgaris was also reported 6 . However, with the increased use of antibiotics, the susceptibility trends of P. acnes have gradually changed and varied from one region to another.…”
Section: Introductionmentioning
confidence: 93%
“…Until the late 1970s, P. acnes was susceptible to different antimicrobials including clindamycin, erythromycin and cyclines 5 . The safe and effective use of azithromycin for treatment of moderate acne vulgaris was also reported 6 . However, with the increased use of antibiotics, the susceptibility trends of P. acnes have gradually changed and varied from one region to another.…”
Section: Introductionmentioning
confidence: 93%
“…The 18 papers that met the inclusion and exclusion criteria [10][11][12][13][14][15][16][17][18][19][20][21][22][23][24][25][26][27] were published across 14 journals, and each represented one RCT, making the number of reviewed RCTs 18. Half of the trials (50 %) were conducted in US or European countries (including a study conducted in the United States, Canada, and Belize and a study in Europe, Mexico, and Australia); the remaining half were conducted in Asian countries.…”
Section: Resultsmentioning
confidence: 99%
“…However, it was previously shown that the basal layer of normal epidermis is usually negative for CK15. [11] Finally, like in any other dermatological pathology, the role of possible confounding factors such the skin type[3435] and age of the patients[36] should be investigated in further studies…”
Section: Discussionmentioning
confidence: 99%