Comparison of sleep in osteoarthritic patients and age and sex matched healthy controls.

Leigh, T. J.; Hindmarch, Ian; Bird, H. A.; Wright, V.

doi:10.1136/ard.47.1.40

Cited by 77 publications

(36 citation statements)

References 12 publications

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“…One small PSG study, however, found that 14 OA patients demonstrated an increase in NREM stage I, a decrease in NREM stage II, and more wake after sleep onset time compared with controls [22]. A report comparing 10 patients with fi bromyalgia to 10 patients with OA found both groups demonstrated similar sleep disturbance profi les, including prolonged sleep latency, prolonged middle awakenings, and frequent alpha intrusion (microarousal) during NREM stage II [23].…”

Section: Sleep Disturbance In Osteoarthritismentioning

confidence: 95%

Mechanisms by which sleep disturbance contributes to osteoarthritis pain: A conceptual model

Smith

Quartana²,

Okonkwo³

et al. 2009

Current Science Inc

125

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Sleep disturbance is prevalent in aging and painful rheumatologic populations, but it has largely been a neglected dimension of the routine clinical care of arthritis patients. Pain associated with osteoarthritis (OA) is a leading cause of disability worldwide, and factors that contribute to pain in OA are poorly understood. Sleep disturbance is not only a consequence of pain, it is also likely to play an integral role in pain expression. Emerging research suggests that many patients with OA demonstrate signs of generalized hyperalgesia and faulty central pain modulatory processing similar to other idiopathic pain disorders, such as fibromyalgia. Sleep disruption is increasingly recognized as a direct contributor to both hyperalgesia and impaired endogenous pain modulation. This article reviews the extant literature on sleep disturbance and hyperalgesia in patients with OA. We propose a conceptual working model describing pathways by which sleep disturbance interacts directly with central pain processing mechanisms and inflammatory processes, and indirectly with mood and physical functioning to augment clinical OA pain. The clinical and research implications of the model are discussed.

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Section: Sleep Disturbance In Osteoarthritismentioning

confidence: 95%

Mechanisms by which sleep disturbance contributes to osteoarthritis pain: A conceptual model

Smith

Quartana²,

Okonkwo³

et al. 2009

Current Science Inc

125

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“…There is growing evidence that sleep is affected as a consequence of physical health, with poor health precipitating or contributing to existing sleep difficulties (7)(8)(9)(10). Arthritis has been found to be associated with sleep problems in a number of studies, although these studies have mainly been conducted on small patient populations and have tended to focus on inflammatory forms of the disease (8,(11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21).…”

Section: Introductionmentioning

confidence: 99%

“…Leigh and colleagues (20) found that when compared with age-and sex-matched controls, male patients with osteoarthritis had more stage 1 sleep (very light stage of sleep similar to drowsiness) and less stage 2 sleep (light sleep). Weekly problems with sleep onset, sleep maintenance, and early morning awakenings were reported by 31%, 81%, and 51% of participants with knee pain (with and without radiographic evidence of osteoarthritis), respectively, in the Observational Arthritis Study in Seniors (22).…”

Section: Introductionmentioning

confidence: 99%

Pain as a mediator of sleep problems in arthritis and other chronic conditions

Power¹,

Perruccio²,

Badley³

2005

Arthritis & Rheumatism

118

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“…Compared to a general population sample of US citizens, patients with OA (n = 152) were shown to be limited in their activities (4). In some studies describing only patients with severe OA, such symptoms were related to a reduced ability to deal with household chores, shopping, and reduced sleep (5)(6)(7). In other studies defining OA by radiographic criteria only, a significant reduction in physical functioning was reported in patients with knee OA (8).…”

mentioning

confidence: 99%

Health‐related quality of life in patients with osteoarthritis in a family practice setting

Bock

Touw-Otten

et al. 1995

Arthritis & Rheumatism

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Objective. To study the impact of osteoarthritis (OA) on all areas of a patient's health-related quality of life.Methods. The Sickness Impact Profile (SIP) was administered to a group of patients with OA selected from a family medicine setting. The results were compared to a reference population, stratified by age, and adjusted for sex.Results. OA was associated with significant impairment, and had an important impact on, healthrelated quality of life in the areas of ambulation, body care and movement, emotional behavior, sleep and rest, home management, and work, especially in patients ages 41-60. The older patients differed less from the controls than did the younger ones. Items that contributed to the differences between OA patients and controls were mainly related to physical limitations.Conclusion. Most dysfunctions related to OA are physical.

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Comparison of sleep in osteoarthritic patients and age and sex matched healthy controls.

Cited by 77 publications

References 12 publications

Mechanisms by which sleep disturbance contributes to osteoarthritis pain: A conceptual model

Mechanisms by which sleep disturbance contributes to osteoarthritis pain: A conceptual model

Pain as a mediator of sleep problems in arthritis and other chronic conditions

Health‐related quality of life in patients with osteoarthritis in a family practice setting

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