Comparison of Retinal Nerve Fiber Layer Thickness Measurements Using Time Domain and Spectral Domain Optical Coherence Tomography, and Visual Field Sensitivity

Takagishi, Mai; Hirooka, Kazuyuki; Baba, Tetsuya; Mizote, Masanori; Shiraga, Fumio

doi:10.1097/ijg.0b013e3181efb371

Cited by 38 publications

(35 citation statements)

References 5 publications

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“…Structurefunction relationships with TD-and SD-OCT were compared previously using different methodologies. Leung et al 25 correlated the mean deviation and average RNFL measurements, and observed no significant difference in the correlation strength for Cirrus OCT and Stratus OCT. Takagishi et al 26 also found similar structure-function relationships using Stratus and Cirrus OCT devices, with significant correlations for all but the nasal sector.…”

Section: Discussionmentioning

confidence: 60%

Structure–Function Correlations in Glaucoma Using Matrix and Standard Automated Perimetry Versus Time-Domain and Spectral-Domain OCT Devices

Pinto

Costa

Melo

et al. 2014

Invest. Ophthalmol. Vis. Sci.

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Section: Discussionmentioning

confidence: 60%

Structure–Function Correlations in Glaucoma Using Matrix and Standard Automated Perimetry Versus Time-Domain and Spectral-Domain OCT Devices

Pinto

Costa

Melo

et al. 2014

Invest. Ophthalmol. Vis. Sci.

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“…The parameter investigated in this study was the global average thickness, corresponding to the average of RNFL thickness measurements obtained in the 360-degree peripapillary circle. This parameter was chosen as it has been reported as having one of the best, if not the best, diagnostic accuracy in previous studies with OCT. 4, 6, 12, 18, 19 Also, this parameter has shown the best reproducibility in previous studies with longitudinal OCT data. 20–22 …”

Section: Methodsmentioning

confidence: 71%

“…Although it could be argued that this approach might introduce bias, the cross-sectional diagnostic accuracy of TDOCT has been reported to be comparable to SDOCT in previous studies. 4, 6, 19, 41 In addition, cases and controls were matched by number of OCT tests during follow-up and we did not attempt to estimate longitudinal changes over time, which could be more problematic when mixing tests from different versions of OCT. It should also be noted that our ability to estimate the lead time was limited by the duration of follow- up of the study.…”

Section: Discussionmentioning

confidence: 99%

Estimating Lead Time Gained by Optical Coherence Tomography in Detecting Glaucoma before Development of Visual Field Defects

et al. 2015

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Purpose To estimate the diagnostic accuracy and lead time gained by retinal nerve fiber layer (RNFL) thickness measurements from optical coherence tomography (OCT) for detecting glaucoma before the development of visual field defects. Design Observational cohort study. Participants The study group included 75 eyes of 75 patients suspected of glaucoma followed as part of the Diagnostic Innovations in Glaucoma (DIGS) study. These eyes had normal standard automated perimetry (SAP) visual fields at baseline and developed repeatable (3 consecutive) abnormal tests during a median follow-up of 6.3 years. A control group of 75 eyes of 75 healthy subjects matched by age and number of OCT tests during follow-up was included. Methods RNFL thickness measurements were obtained at the time of development of the earliest SAP defect (Time 0) and also at times −1, −2, −3, etc., corresponding to one year, two years, three years, etc., before the development of field loss. OCT measurements at corresponding time intervals were analyzed for controls. Time-dependent receiver operating characteristic (ROC) curves were used to evaluate diagnostic accuracy of OCT. Main Outcome Measures ROC curve areas and sensitivities at fixed specificities at different times before development of field loss. Results At the date of conversion to the earliest visual field defect (Time 0), mean ± SD average RNFL thickness was 75.0 ± 9.8µm in glaucomatous eyes and 90.6 ± 8.0µm for controls (P<0.001). Significant differences were seen up to 8 years before development of visual field defects (86.3 ± 8.2µm versus 91.4 ± 7.6µm, respectively; P=0.021). ROC curve areas decreased with increasing times before detection of field defects. At times 0, −4 and −8 years, ROC curve areas were 0.87, 0.77 and 0.65, respectively. At 95% specificity, up to 35% of eyes had abnormal average RNFL thickness 4 years before development of visual field loss, and 19% of eyes had abnormal results 8 years before field loss. Conclusion Assessment of RNFL thickness with OCT was able to detect glaucomatous damage before the appearance of visual field defects on SAP. In many subjects, significantly large lead times were seen when applying OCT as an ancillary diagnostic tool.

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“…Results of these studies have demonstrated there are high correlations between the global VF sensitivity and the peripapillary RNFL/GCC thickness. 5,11,12 The macular VF, including the central vision, is very important if a glaucoma patient is to enjoy normal daily life. Therefore, preservation of the macular VF is the key concern in glaucoma management.…”

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confidence: 99%

Correlation Between the Ganglion Cell-Inner Plexiform Layer Thickness Measured With Cirrus HD-OCT and Macular Visual Field Sensitivity Measured With Microperimetry

Sato¹,

Hirooka²,

Baba³

et al. 2013

Invest. Ophthalmol. Vis. Sci.

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Comparison of Retinal Nerve Fiber Layer Thickness Measurements Using Time Domain and Spectral Domain Optical Coherence Tomography, and Visual Field Sensitivity

Abstract: The structure-function relationship was comparable between Cirrus HD-OCT and Stratus OCT RNFL measurements.

Cited by 38 publications

References 5 publications

Structure–Function Correlations in Glaucoma Using Matrix and Standard Automated Perimetry Versus Time-Domain and Spectral-Domain OCT Devices

Structure–Function Correlations in Glaucoma Using Matrix and Standard Automated Perimetry Versus Time-Domain and Spectral-Domain OCT Devices

Estimating Lead Time Gained by Optical Coherence Tomography in Detecting Glaucoma before Development of Visual Field Defects

Correlation Between the Ganglion Cell-Inner Plexiform Layer Thickness Measured With Cirrus HD-OCT and Macular Visual Field Sensitivity Measured With Microperimetry

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