No abstract

Trabeculectomy might decrease not only the IOP in the sitting position but also the magnitude of IOP elevation associated with the postural change.

The structure-function relationship was comparable between Cirrus HD-OCT and Stratus OCT RNFL measurements.

ABSTRACT.Purpose: To investigate the relationship between filtering bleb function and Stratus optical coherence tomography (OCT) images. Methods: We studied 72 eyes of 65 consecutive patients who had a fornixbased conjunctival flap in primary trabeculectomy with mitomycin C (MMC). Filtering blebs with various types of glaucoma were examined using Stratus OCT. Success rates were defined as intraocular pressure (IOP) £ 15 mmHg and IOP reduction ‡ 25% without medication or additional surgery. Success rates among classified groups were compared using Kaplan-Meier survival curves and the log-rank test. Results: Blebs were classified into three different categories on the basis of the following Stratus OCT patterns: cystoid type (multiple cysts inside the bleb; 17 eyes), diffuse type (low to high reflective areas that were mixed inside the bleb; 31 eyes) and layer type (medium to high reflective layer inside the bleb; 24 eyes). Success rates in the cystoid-, diffuse-and layer-type blebs were 94%, 97% and 75% (P = 0.02), respectively. Conclusion: In trabeculectomy with MMC and a fornix-based conjunctival flap, there is a significant association between the success rates and the postoperative Stratus OCT findings of filtering blebs.

Secondary glaucoma, excessive filtration, and no performance of laser suturolysis after trabeculectomy might be risk factors for development of avascular filtering blebs in primary fornix-based trabeculectomy.