Comparison of pulmonary function test and computed tomography volumetry in living lung donors

Chen, Fengshi; Kubo, Takeshi; Tanaka, Shōji; Fujinaga, Takuji; Bando, Toru; Date, Hiroshi

doi:10.1016/j.healun.2010.11.019

Cited by 53 publications

(28 citation statements)

References 20 publications

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“…Investigators tested pulmonary function by using a Minato System 21 (Minato Medical Science Co Ltd., Osaka, Japan) to measure forced vital capacity (FVC) and forced expiratory volume in 1 s (FEV 1 ). We applied a prediction method by using calculated FVC according to the number of resected segments to postoperative spirometric parameters as we reported previously .…”

Section: Methodsmentioning

confidence: 99%

A Prospective Study Analyzing One-Year Multidimensional Outcomes in Living Lung Transplant Donors

Chen

Oga

Sakai

et al. 2013

American Journal of Transplantation

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The success of living‐donor lobar lung transplantation (LDLLT) largely depends on donor outcome; but to date, no authors have studied health‐related quality of life (HRQOL) of donors. We prospectively evaluated multidimensional outcomes before and 1 year after donor lobectomies. Patient‐reported HRQOL, dyspnea, psychological status and sleep quality, and physiological pulmonary function were determined. All donors were alive without any limitations in their activities of daily living after 1 year. Postoperative pulmonary function was better than the estimated preoperative values; but, with respect to HRQOL, four of the eight subscales of the Medical Outcomes Study 36‐item short form (SF‐36) deteriorated significantly after donation. In addition, dyspnea assessed by the modified Medical Research Council scale also worsened significantly. In contrast, postoperative anxiety assessed by the Hospital Anxiety and Depression Scale significantly improved from baseline. The donors whose recipients died reported lower SF‐36 scores with worsening sleep quality measured by Pittsburgh Sleep Quality Index. Thus, although postoperative pulmonary functions in donors were preserved, their HRQOL and dyspnea deteriorated postoperatively. Moreover, HRQOL and sleep quality were impaired in recipients who experienced poor outcomes. To capture the comprehensive outcomes in LDLLT donors after donation, patient‐reported outcomes should be analyzed separately from physiological outcomes.

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Section: Methodsmentioning

confidence: 99%

A Prospective Study Analyzing One-Year Multidimensional Outcomes in Living Lung Transplant Donors

Chen

Oga

Sakai

et al. 2013

American Journal of Transplantation

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“…The 3D‐CT volumetry is a newly developed method for size matching in LDLLT that allows us to calculate the whole lung volume and also allows us to calculate the volume of a particular part of the lung, e.g. a single lobe.…”

Section: Methodsmentioning

confidence: 99%

“…3D‐CT volumetric data are true volume data and can also be used for size matching in LDLLT . We have previously reported that certain pulmonary function test (PFT) results are well correlated with 3D‐CT volumetric data in healthy subjects .…”

Section: Introductionmentioning

confidence: 99%

Adaptation Over a Wide Range of Donor Graft Lung Size Discrepancies in Living-Donor Lobar Lung Transplantation

Chen

Kubo

Yamada

et al. 2013

American Journal of Transplantation

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“…Donor selection criteria are outlined in Table 1. For size accommodation during the LDLLT, we used our previously proposed method that calculated forced vital capacity (FVC) by the number of segments [2,7–9]. Given that the right lower lobe consists of 5 segments, the left lower lobe consists of 4, and the whole lung consists of 19, we estimated the graft FVC with the following equation: Graft FVC = measured FVC of the right donor × 5/19 + measured FVC of the left donor × 4/19.…”

Section: Methodsmentioning

confidence: 99%

Short-term outcome in living donors for lung transplantation: the role of preoperative computer tomographic evaluations of fissures and vascular anatomy

Chen¹,

Fujinaga²,

Tanaka³

et al. 2012

Transplant International

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Summary Successful living‐donor lobar lung transplantation (LDLLT) largely depends on donor outcome. We reviewed our experiences with LDLLT and focused on preoperative computed tomographic evaluations of donors. Twenty‐five LDLLTs were performed in Kyoto University. As a routine preoperative assessment, high‐resolution chest computed tomography (CT), and three‐dimensional (3D)‐CT angiography were performed. Preoperative evaluations, surgical procedures, and early postoperative outcomes were reviewed in 43 consecutive LDLLT donors. All donors were discharged home after the donor lobectomies. Severely incomplete fissures were intraoperatively identified in two donors, whose interlobar fissures were mostly not identified by high resolution CT preoperatively. Preoperative 3D‐CT angiography was effective for the identification of the branches of the pulmonary artery and vein. Pulmonary arterioplasties were performed with auto pericardial patches in three left donors. The bilateral donors had to be exchanged because of an anomaly of the pulmonary veins in one donor. Small pulmonary arterial branches to the remaining lobes were to be sacrificed in 23 donors (53%). Early postoperative complications were ascertained in seven donors, and five of them presented air leak‐related complications. Living donor lobectomies were safely performed with low morbidities in our institution. Preoperative computer tomographic evaluations might be useful in donor lobectomies.

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Comparison of pulmonary function test and computed tomography volumetry in living lung donors

Cited by 53 publications

References 20 publications

A Prospective Study Analyzing One-Year Multidimensional Outcomes in Living Lung Transplant Donors

A Prospective Study Analyzing One-Year Multidimensional Outcomes in Living Lung Transplant Donors

Adaptation Over a Wide Range of Donor Graft Lung Size Discrepancies in Living-Donor Lobar Lung Transplantation

Short-term outcome in living donors for lung transplantation: the role of preoperative computer tomographic evaluations of fissures and vascular anatomy

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