Comparison of prevalence of anti‐hepatitis C virus antibodies in differing South American populations

Robinson, John W.; Rosas, Marcela; Guzmán, Fanny; Patarroyo, Manuel Elkín; Moreno, Alberto Díaz

doi:10.1002/(sici)1096-9071(199610)50:2<188::aid-jmv13>3.3.co;2-b

Cited by 4 publications

(4 citation statements)

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“…Our investigation is in agreement with previous work (118–121). However, our analysis was performed at the country level, rather than at the regional level, because of lack of adequate representative regional studies and the absence of surveillance programmes.…”

Section: Discussionsupporting

confidence: 94%

Trends and projections of hepatitis C virus epidemiology in Latin America

Kershenobich¹,

Razavi²,

Sánchez-Ávila³

et al. 2011

Liver International

132

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Background and aim: The purpose of the present investigation is to provide an analysis of previous works on the epidemiology of the hepatitis C virus (HCV) infection from six countries throughout Latin America, to forecast the future HCV prevalence trends in Argentina, Brazil, Mexico and Puerto Rico, and to outline deficiencies in available data, highlighting the need for further research. Methods: Data references were identified through indexed journals and non-indexed sources. Overall, 1080 articles were reviewed and 150 were selected based on their relevance to this work. When multiple data sources were available for a key assumption, a systematic process using multi-objective decision analysis (MODA) was used to select the most appropriate sources. When data were missing, analogues were used. Data from other countries with similar risk factors and/or population compositions were used as a proxy to help predict the future trends in prevalence. Results: The review indicates that the dominant genotype is type 1. HCV prevalence in the analysed countries ranges from 1 to 2.3%. The Latin American countries have been very proactive in screening their blood supplies, thus minimizing the risk of transmission through transfusion. This suggests that other risk factors are set to play a major role in continued new infections. The number of diagnosed and treated patients is low, thereby increasing the burden of complications such as liver cirrhosis or hepatocellular carcinoma. The HCV prevalence, according to our modelling is steady or increasing and the number of infected individuals will increase. Conclusions: The results herein reported should provide a foundation for informed planning efforts to tackle hepatitis.

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Section: Discussionsupporting

confidence: 94%

Trends and projections of hepatitis C virus epidemiology in Latin America

Kershenobich¹,

Razavi²,

Sánchez-Ávila³

et al. 2011

Liver International

132

View full text Add to dashboard Cite

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“…In contrast, the infection is almost absent from all the Amerindian communities studied in both the Amazon Plain and the Andean Highlands, as shown by studies in Venezuela, Bolivia, French Guiana, andBrazil (Blitz-Dorfman et al, 1994, 1996;de Paula et al, 2001;León et al, 1999;Soares et al, 1994;Talarmin et al, 1997). However, anti-HCV prevalence ranging from 0.5 to 2.5% has been found among Amerindians in Colombia (Robinson et al, 1996), three remote areas of Brazil (Aguiar et al, 2002;de Paula et al, 2001;Soares et al, 1994), and the Orinoco Basin (Aguilar et al, 2001), meaning that the introduction of HCV into remote Amazonian communities is already occurring. The resulting impact on health in the future is difficult to predict.…”

Section: Epidemiology Of Hcv Infectionmentioning

confidence: 88%

Epidemiology of viruses causing chronic hepatitis among populations from the Amazon Basin and related ecosystems

Echevarría

León

2003

Cad. Saúde Pública

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On the last twenty years, viral hepatitis has emerged as a serious problem in almost all the Amerindian communities studied in the Amazon Basin and in other Amazon-related ecological systems from the North and Center of South America. Studies performed on communities from Bolivia, Brazil, Colombia, Peru and Venezuela have shown a high endemicity of the hepatitis B virus (HBV) infection all over the region, which is frequently associated to a high prevalence of infection by hepatitis D virus among the chronic HBV carriers. Circulation of both agents responds mainly to horizontal virus transmission during childhood through mechanisms that are not fully understood. By contrast, infection by hepatitis C virus (HCV), which is present in all the urban areas of South America, is still very uncommon among them. At the moment, there is not data enough to evaluate properly the true incidence that such endemicity may have on the health of the populations affected. Since viral transmission might be operated by mechanisms that could not be acting in other areas of the World, it seems essential to investigate such mechanisms and to prevent the introduction of HCV into these populations, which consequences for health could be very serious.

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“…El primer estudio corresponde al análisis de 1 033 muestras de donantes obtenidas en cinco bancos de sangre de Medellín en 1989; la prevalencia de anti-VHC fue de 0,97% (10/1 033) (14). Otros estudios realizados entre 1995 y 1997 informan una prevalencia de anticuerpos anti-VHC entre 0,9 y 2,3% en donantes de sangre de diferentes ciudades del país (14)(15)(16)25,26).…”

Section: Resultsunclassified

Epidemiología de la infección por el virus de la hepatitis C en Colombia

Lopez-Osorio

Beltrán

Navas

2021

Revista Panamericana De Salud Pública

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Objetivo. Describir la epidemiología de la infección por el virus de la hepatitis C (VHC) en Colombia. Métodos. Revisión crítica de los estudios de epidemiología de la infección por VHC en Colombia mediante búsqueda de artículos originales y revisiones de tema publicados en el período 1989 a 2020 en las bases de datos PubMed, SciELO y ScienceDirect. Además, se revisaron los informes del Instituto Nacional de Salud y de la Cuenta de Alto Costo del Ministerio de Salud y Protección Social. Resultados. Los datos de seroprevalencia de anticuerpos anti-VHC en donantes de sangre están en un rango de 1,5% a 0,32%, que corresponden a los informes del inicio y el final del período de estudio, respectivamente. En la población con factores de riesgo se observa una alta prevalencia de infección por VHC, aunque con variaciones a lo largo del tiempo. Con respecto a los genotipos de VHC en Colombia, se han identificado los genotipos 1, 2, 3 y 4 (subgenotipos 1a, 1b, 2a y 3a). Conclusiones. En el período de observación, se describe una disminución en la seroprevalencia de la infección por VHC en donantes de sangre y en pacientes en tratamiento con hemodiálisis en Colombia, lo que demuestra el impacto de las políticas de sangre segura y las medidas de bioseguridad. Los estudios en personas que usan drogas ilícitas por vía inyectable indican una alta prevalencia de infección, con diferencias según la región del país. El genotipo 1, subgenotipo 1b, del VHC es el más frecuente en los distintos estudios realizados en Colombia, y el informe más reciente de la Cuenta de Alto Costo del Ministerio de Salud y Protección Social señala que el genotipo 4 es el segundo genotipo más frecuente en el país.

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Comparison of prevalence of anti‐hepatitis C virus antibodies in differing South American populations

Cited by 4 publications

References 0 publications

Trends and projections of hepatitis C virus epidemiology in Latin America

Trends and projections of hepatitis C virus epidemiology in Latin America

Epidemiology of viruses causing chronic hepatitis among populations from the Amazon Basin and related ecosystems

Epidemiología de la infección por el virus de la hepatitis C en Colombia

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