Comparison of Odor Perception in Humans and Animals

Walker, Judy; Jennings, Roger A.

doi:10.1007/978-3-642-76223-9_13

Cited by 27 publications

(19 citation statements)

References 42 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Specifically, this has been observed clinically [8], using both psychophysical [14] and behavioral measures of trigeminal function [7], and by means of electrophysiological techniques [6]. The present results also compare to those of Walker and Jennings [15], who reported an increase in nasal irritation thresholds for acetic acid, propionic acid and amyl acetate in anosmics. In addition, similar findings had already been obtained in experimental animals [16][17][18].…”

Section: Discussionsupporting

confidence: 74%

Decreased Trigeminal Sensitivity in Anosmia

Gudziol

Schubert

Hummel³

2001

ORL

View full text Add to dashboard Cite

The present study aimed to investigate intranasal trigeminal sensitivity in a large sample of patients with anosmia due to different etiologies. We investigated the trigeminal detection threshold for formic acid in healthy controls (n = 96) and patients with anosmia due to head trauma (n = 18) or sinonasal disease (n = 54). Anosmics exhibited higher thresholds compared with normosmics (p < 0.001). In addition, thresholds were found to be higher in patients with posttraumatic anosmia compared to anosmics with sinonasal disease (p < 0.001). The data indicate that (1) loss of olfactory sensitivity in humans may be associated with a decreased sensitivity towards trigeminal stimuli and (2) alteration of intranasal trigeminal function is stronger in patients with posttraumatic anosmia compared to patients with sinonasal disease. This may have implications for the medicolegal investigation of anosmic patients where trigeminal stimuli are frequently used to assess the patient’s response bias.

show abstract

Section: Discussionsupporting

confidence: 74%

Decreased Trigeminal Sensitivity in Anosmia

Gudziol

Schubert

Hummel³

2001

ORL

View full text Add to dashboard Cite

show abstract

“…This approach is, however, not entirely straightforward since it has been shown that loss of olfactory function per se changes the responsiveness to intranasal trigeminal stimuli of anosmic subjects (Kobal and Hummel, 1988;Walker and Jennings, 1991;Hummel et al, 1996;Gudziol et al, 2001). There are, however, techniques available that allow for assessment of trigeminal chemosensory function in normosmic controls.…”

Section: Odorants Activate the Trigeminal Systemmentioning

confidence: 94%

Interactions between the chemical senses: Trigeminal function in patients with olfactory loss

Frasnelli¹,

Hummel²

2007

International Journal of Psychophysiology

View full text Add to dashboard Cite

“…Both human and animal studies support the general view that the olfactory system is more sensitive to chemicals than the trigeminal system (Doty, 1975(Doty, , 1978Henton, Smith, and Tucker, 1969;Walker and Jennings, 1991;Walker, Tucker, and Smith, 1979). Some attempts to separate odor responses from nasal pungency (i.e., irritant) responses entailed instructing subjects to focus on one type of sensation and ignore the other (e.g., Cometto-Muñiz, García-Medina, and Calviño, 1989;Cometto-Muñiz and Hernández, 1990).…”

Section: B Functional Dissociation Of Trigeminal and Olfactory Respomentioning

confidence: 97%