Comparison of naturally occurring and ligature‐induced peri‐implantitis bone defects in humans and dogs

Abstract

Within the limits of the present study, it might be concluded that configurations and sizes of ligature-induced peri-implantitis bone defects in dogs seemed to resemble naturally occurring lesions in humans.

Pre-clinical Models for Oral and Periodontal Reconstructive Therapies

“…Ligatures are typically removed after 2-3 mos, when approximately 30-50% of bone support is lost. Peri-implant bone defects are circumferential and wide, but rarely result in shallow craters (Lindhe et al, 1992;Grunder et al, 1993;Nociti et al, 2001a;Schwarz et al, 2007). The microflora associated with experimental peri-implantitis demonstrates many similarities to natural peri-implantitis lesions (Nociti et al, 2001b;Shibli et al, 2003).…”

¿Cuál es la indicación y eficacia de la terapia quirúrgica regenerativa en el tratamiento de la periimplantitis?

“…Los resultados de un reciente artículo mostró muchas similitudes entre las configuraciones y tamaños de los defectos óseos periimplantarias inducidos por ligadura en perros y los defectos que ocurren naturalmente en los humanos (Schwarz et al, 2007) declarando así el modelo animal como un modelo viable para la valoración de la eficacia de la regeneración periimplantaria.…”

“…Además, en los defectos de clase I, la posición de la componente intraósea, con respecto al cuerpo del implante, nos permite identificar cinco configuraciones diferentes. Estas diferencias se basan en el ancho de la componente vertical, horizontal y de la componente intraóseos circunferencial o de la combinación entre las diferentes componentes (Schwarz et al, 2007). Los resultados mostraron que los defectos periimplantarios de clase Ie (componente intraóseos circunferencial puro) son la configuración más común tanto en humanos como en animales.…”

Comparison of a Hydroxyapatite-Coated and an Anodic Oxidized Titanium Implant for Experimentally Induced Peri-Implantitis: Macroscopic and Novel Radiographic Evaluations in a Canine Model

“…Consequently, inflammatory lesions formed rapidly at the ligature sites, and bone loss occurred 13,14) . The configurations and sizes of ligature-induced peri-implantitis bone defects in dogs appeared to resemble naturally occurring lesions in humans 12) . However, no differences in the implant types were reported following the animal studies [15][16][17][18] .…”

“…Canine and primate models have been used to study mechanisms involved in the development and progression of periimplantitis 11,12) . In prior animal models, ligatures constructed of cotton or silk were placed around properly integrated implants and adjusted in the submarginal position, which promoted the buildup of plaque around the neck of the implant.…”