Comparison of mental and physical health between patients with primary and secondary Raynaud's phenomenon Category: Article

Fábián, Balázs; Fábián, Anna; Csiki, Zoltán

doi:10.1016/j.jpsychores.2018.11.001

Cited by 5 publications

(4 citation statements)

References 44 publications

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“…Irrespective of the underlying cause, RP has a significant negative impact on individuals' quality of life and can result in persistent digital ischaemia including ulceration and gangrene in secondary forms of RP (Fig 2). [1][2][3][4] The purpose of this review is to describe the relevant epidemiology and pathogenesis, clinical features including complications, and provide a practical approach to the investigation and multi-faceted management of RP.…”

Section: Introductionmentioning

confidence: 99%

Raynaud's phenomenon

Haque

Hughes

2020

Clinical Medicine

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Section: Introductionmentioning

confidence: 99%

Raynaud's phenomenon

Haque

Hughes

2020

Clinical Medicine

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“…2 Significantly more patients with secondary RP had anxiety and depressive symptoms than patients with primary RP (43.9% vs 23.3% and 31.7% vs 11.7%, respectively). 66 Patients with secondary RP have a poorer physical health condition and RP -specific QoL than patients with primary RP. 66 The severity of RP had one of the strongest associations with reduced hand function in SSc.…”

Section: Monitoring Of Patients With Primary Raynaud Phenomenon For Tmentioning

confidence: 99%

“…66 Patients with secondary RP have a poorer physical health condition and RP -specific QoL than patients with primary RP. 66 The severity of RP had one of the strongest associations with reduced hand function in SSc. 67 Therefore, anxiety, depression, and reduced QoL should be considered when managing all patients with RP.…”

Section: Monitoring Of Patients With Primary Raynaud Phenomenon For Tmentioning

confidence: 99%

Recent advances in the workup and management of Raynaud’s phenomenon

Lis‐Święty

2019

Polish Archives of Internal Medicine

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oxide synthase 1 gene as significantly correlated with RP in the general population. 4 Major risk factors for primary RP include, in addition to the female sex and family history, a previous sensation of cold hands, migraine, cardiovascular diseases, decreased body mass index, manual occupation (not including vibration tool use), and estrogen replacement therapy. 3-6 Cigarette smoking and alcohol consumption are still of unclear significance when concerning the prevalence of primary RP. 7 Secondary RP associated with a known disease, mainly with systemic sclerosis (SSc) (>80% of patients) or other connective tissue diseases (CTDs), is rare and accounts for 10% to 20% of all RP cases. 8 Other common causes of secondary RP include diseases of arteries in the upper limbs (60% of RP occurring in individuals older than 60 years), malignancies, endocrine diseases, occupational syndromes, hematologic disorders, and infections (TABLE 1). 8,9 In addition, several Introduction Raynaud phenomenon (RP) is defined as recurrent, reversible episodes of vasospasm involving peripheral small vessels of the fingers and toes, at times also of the other acral sites (nose, ears, oral mucosa, lips, or nipples), when exposed to a cold environment or stressful situation. 1 This is characterized by a series of color changes in the affected area: first white (lack of blood flow), then bluish (deoxygenation of remaining blood), and red (reperfusion). Attacks can cause distal pain, burning, numbness, and paresthesia. 2 Regarding its etiology, RP is classified as primary (idiopathic) or secondary. Primary RP, which is an isolated finding without an underlying pathology, is common, occurring in about 5% of the general population living in areas with cold climates. 3 The prevalence of RP is higher in women (female-to-male ratio of 9 to 1). There is an associated genetic predisposition: one polymorphic variant was identified within the nitric

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“…Furthermore, we would suggest that studies are conducted to investigate functioning in all dimensions as described in the International Classification of Functioning framework 11 including impairments in body functions, activity limitations, and participation restrictions. To note, emotional functions are affected in individuals with primary RP, 12 which needs consideration.…”

Section: What Are the Implications Of The Cochrane Evidence For Practice In Rheumatology?mentioning

confidence: 99%

What are the effects of vasodilators in patients with primary Raynaud’s phenomenon? A Cochrane review summary with commentary

Benlidayı

2021

Int J of Rheum Dis

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Comparison of mental and physical health between patients with primary and secondary Raynaud's phenomenon Category: Article

Cited by 5 publications

References 44 publications

Raynaud's phenomenon

Raynaud's phenomenon

Recent advances in the workup and management of Raynaud’s phenomenon

What are the effects of vasodilators in patients with primary Raynaud’s phenomenon? A Cochrane review summary with commentary

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