Comparative Study of Thyroid Abnormalities With Severity of Chronic Renal Failure

Shamsuddin, M.; Makandar, Asmabi

doi:10.14260/jemds/2015/1997

Cited by 3 publications

(3 citation statements)

References 15 publications

(16 reference statements)

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“…Though, the blunted hormone response also suggests disordered function at the hypothalamicpituitary level that can be prompted by uremic toxins. When compared to normal, patients with chronic renal failure have an attenuated rise in TSH levels during the evening hours and the normally pulsatile secretion of TSH is smaller in amplitude (Shamsuddinn, 2015).…”

Section: Introductionmentioning

confidence: 95%

Study on Thyroid Function Tests in Hemodialysis Patients of Iraq

Abdalla¹,

Hassan²,

Al-Mallah³

2018

Int. J. Curr. Res. Biosci. Plant Biol.

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This study was designed to find the frequency of different abnormalities that can be observed in the results of thyroid function tests in patients with chronic renal failure, who are on hemodialysis, to assess the effect of having chronic renal failure on these frequencies, and to assess effect of age, duration of chronic renal failure, total serum protein level and serum albumin level of the results of thyroid function tests in patients with chronic renal failure, who are on hemodialysis. So that 35 patients with chronic renal failure and on hemodialysis had been randomly selected from those who attended the hemodialysis unit at Al-Yarmouk Teaching Hospital during the period from July 2016 to February 2017. Age and sex matched control had been selected randomly (35 patients).detailed questionnaire had been applied containing information about the personal information and risk factors. All of the patients investigated for thyroid function tests and total serum protein and serum albumin levels. This study had shown there is general tendency of all thyroid function tests to be low but with the normal range, this tendency had been shown according to age, duration of chronic renal failure, level of serum albumin and total serum protein. Lower T3 levels are associated statistically with older age, and lower serum albumin levels. Lower TSH is associated with older age and higher total serum protein levels.

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Section: Introductionmentioning

confidence: 95%

Study on Thyroid Function Tests in Hemodialysis Patients of Iraq

Abdalla¹,

Hassan²,

Al-Mallah³

2018

Int. J. Curr. Res. Biosci. Plant Biol.

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“…Several investigations of thyroid function in uremic patients have been conducted, with varying outcomes. Various workers have documented hypothyroidism, hyperthyroidism, and euthyroidism [8] . Under physiological settings, glomerular filtration removes iodine from circulation, which is a key component in the creation of thyroid hormone.…”

Section: Introductionmentioning

confidence: 99%

A Cross-sectional Study on the Evaluation of Thyroid Hormone Levels and Lipid Profile in Chronic Kidney Disease Patients and to Establish Their Correlation with Disease Severity

Sharma

Patidar

Jadon

et al. 2022

International Journal of Medical Arts

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Article informationBackground: Chronic kidney disease [CKD] is linked to poor kidney function and a persistent decrease in glomerular filtration rate. Almost no lipid profile anomalies in CKD to patho-physiologically notable variations in lipid profile in patients with CKD such as raised triglycerides and low high-density lipoprotein levels have been reported in Indian research proving the pathophysiological link of CKD with Lipid profile. Aim of the Study:To estimate the thyroid hormone level and lipid profile in chronic kidney disease patients and to establish a correlation between them.Patients and Methods: CKD patients with moderate to severe disease, irrespective of gender, within the age groups 20-90 years were included in the study. Moderate CKD [stage 3] is defined as an estimated glomerular filtration rate [eGFR] of 30-60 ml/min, whereas severe CKD [stages 4 and 5] is defined as an eGFR of less than 30 ml/min & patients on maintenance hemodialysis were included. Blood urea, Serum creatinine, Lipid profile, TSH, total T3, and total T4 values of subjects were obtained and analysed. CKD staging was done on eGFR.Results: Our study included 123 CKD patients who met the criteria for the disease. 95 % of the patients had high TSH levels, 48% had low T3 levels, and 95 % had low T4 levels. Out of 123 patients, 87% [N=108] patients had deranged lipid profiles. Conclusion:The study concluded that there is statistically significant association between Chronic Kidney disease and deranged lipid and thyroid profiles and hypothyroid state.

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“…Though, the blunted hormone response also suggests disordered function at the hypothalamic-pituitary level that can be prompted by uremic toxins. When compared to normal, patients with chronic renal failure have an attenuated rise in TSH levels during the evening hours and the normally pulsatile secretion of TSH is smaller in amplitude (Shamsuddinn, 2015). There is considerable clinical overlap between chronic renal failure and hypothyroidism.…”

Section: Introductionmentioning

confidence: 99%

Study the Thyroid Function Tests in Hemodialysis Iraqi Patients

Abdalla¹,

Hassan²,

Al-Mallah³

2018

JBLS

View full text Add to dashboard Cite

This study was designed to find the frequency of different abnormalities that can be observed in the results of thyroid function tests in patients with chronic renal failure, who are on hemodialysis, to assess the effect of having chronic renal failure on these frequencies, and to assess effect of age, duration of chronic renal failure, total serum protein level and serum albumin level of the results of thyroid function tests in patients with chronic renal failure, who are on hemodialysis. So that 35 patients with chronic renal failure and on hemodialysis had been randomly selected from those who attended the hemodialysis unit at Al-Yarmouk Teaching Hospital during the period from July 2016 to February 2017, Age and sex matched control had been selected randomly (35 patients). Detailed questionnaire had been applied containing information about the personal information and risk factors. 2 investigated for thyroid function tests and total serum protein and serum albumin levels. This study had shown there is general tendency of all thyroid function tests to be low but with the normal range, this tendency had been shown according to age, duration of chronic renal failure, level of serum albumin and total serum protein. Lower T3 levels are associated statistically with older age, and lower serum albumin levels. Lower TSH is associated with older age and higher total serum protein levels.

show abstract

Comparative Study of Thyroid Abnormalities With Severity of Chronic Renal Failure

Cited by 3 publications

References 15 publications

Study on Thyroid Function Tests in Hemodialysis Patients of Iraq

Study on Thyroid Function Tests in Hemodialysis Patients of Iraq

A Cross-sectional Study on the Evaluation of Thyroid Hormone Levels and Lipid Profile in Chronic Kidney Disease Patients and to Establish Their Correlation with Disease Severity

Study the Thyroid Function Tests in Hemodialysis Iraqi Patients

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