Comparative study of computed tomography guided fine needle aspiration cytology and trucut biopsy in diagnosis of lung cancer: a report of 81 cases

Sharma, Rishi; Chhabra, Gaurav; Luhadia, Atul; Sharma, Sanjeev Kumar; Luhadia, Shanti Kumar

doi:10.18203/2320-6012.ijrms20160522

Cited by 3 publications

(1 citation statement)

References 9 publications

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“…[3,4] Bronchoscopy is useful to obtain biopsy sample in centrally situated lesions while computed tomographic guided transthoracic procedure is useful in peripherally located lesions. [5] Flexible bronchoscopy has high sensitivity for the diagnosis of central lesions but low sensitivity for the peripheral lesions. [6] FNAC was first used by Martin & Ellis as a diagnostic tool.…”

Section: Introductionmentioning

confidence: 99%

Yield of Computed Tomography Guided Fine Needle Aspiration in Diagnosis of Suspected Cases of Lung Cancer: Experience of a Tertiary Care Hospital of North India

Kumar

Yadav

Verma

2021

Gal Int J Health Sci Res

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Background: Lung cancer is the most commonly diagnosed malignancy across the globe. CT guided FNAC of suspicious lung masses is a widely accepted and simple diagnostic method of relatively low cost with minimal complications. Methods: It was a prospective study conducted from February 2018 to February 2019 in PGIMS, Rohtak on thirty two patients of either sex having lung cancer suspected clinically or on Chest X-ray/CT Thorax who were subjected to computed tomography guided fine needle aspiration. Results: Most of the patients (79.98%) were in 41-70 years age group with 81.25% male 18.75% females and M:F 4:1. Mass was located on right side in 59% and on left side in 41% cases. Malignancy was diagnosed in 29(90.62%) cases whereas 3(9.37%) cases were inflammatory. Two patients (6.25%) had small cell carcinoma whereas 26 patients (65.62%) had non-small cell carcinoma. Out of these 26 patients, 14 had squamous cell carcinoma, 9 had adenocarcinoma and 3 had large cell carcinoma. One patient was found to have small round cell tumor. 3 patients (9.37%) had pneumothorax as a complication out of which two required chest tube drainage. Conclusions: CT guided FNAC is a simple, safe, and reliable procedure with high diagnostic accuracy for the diagnosis and sub typing of lung cancer. Though complications are rare, pneumothorax and hemoptysis are occasionally encountered but resolve with active management. Keywords: Lung Cancer; FNAC; CT Guided; Pneumothorax.

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Section: Introductionmentioning

confidence: 99%

Yield of Computed Tomography Guided Fine Needle Aspiration in Diagnosis of Suspected Cases of Lung Cancer: Experience of a Tertiary Care Hospital of North India

Kumar

Yadav

Verma

2021

Gal Int J Health Sci Res

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The diagnostic utility of squash smear cytology in lung malignancies

et al. 2022

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Background Lung malignancy is the most common cause of death worldwide. The main role of pathologist is to differentiate small cell from other cell types as treatment and prognosis varies. Although histopathology is routinely done, squash smears yield better cytomorphology. Aims and objectives To study the clinical history, evaluate the diagnostic yield by means of cytology and histopathology correlation followed by determination of sensitivity and specificity of squash smear cytology for detection of lung malignancies. Materials and methods The present study was an observational analytical study conducted over a period of 3.5 years. Total 60 squash smears were obtained by computed tomography-/bronchoscopy-guided biopsy and stained with Papanicolaou and May-Grunwald stain. Squash smears were correlated with histopathological findings. Statistical analysis Statistics in the form of sensitivity, specificity, positive predictive value, negative predictive value, positive likelihood ratio, and negative likelihood ratio were done. Results Out of total 60 cases, 71.67% cases were males and 65% cases were smokers. Right lung was mostly involved (65%). The major symptom noted was dyspnea on exertion (90%). In 66.7% cases, malignancy was reported while in 10% suspicious and in 23.3% negative for malignancy. The most common malignancy diagnosed was squamous cell carcinoma (18.3%). The sensitivity and specificity of 92.1% and 83.3% were calculated respectively for squash smear, while the positive predictive value (PPV) was 94.6% and the negative predictive value (NPV) was 76.9%. Conclusion Squash smear cytology utilization in diagnosis of lung malignancy is a simple, fast, and reliable procedure with good sensitivity and specificity. It can be used as complementary to histopathology when need arises.

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A Study of Histocytological Findings of Lung Lesions in Image Guided Fnac and Biopsy in Tertiary Care Centre

Gahine

Patre

et al. 2020

ijsr

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Aims and Objectives: To study the cytological and histological findings of lung masses and correlate findings with clinical and radiological findings. Material and methods: The study was an observational study, comprised of two years of prospective from December 2017 to September 2019 and five years of retrospective study between October 2012 to November 2017, conducted in Histopathology & Cytology laboratory, Department of Pathology, Pt. J.N.M. Medical College & Dr. B.R.A.M. Hospital, Raipur, (C.G.), a tertiary referral center. Result: Total 104 cases were studied . Out of 104 lung lesions 74 (71.2%) were males and 30 (28.8%) were females with M:F of 2.46:1. Majority of lung lesions were seen in the age group of 61-70 years i.e. 35 (33.66%) and 51-60 years i.e. 30 (28.85%) followed by 41-50 years 17 (16.35%). Mean age of the patients in our study was 56.4 years. Smoking was the most common predisposing factor for lung carcinoma observed in 58 (55.77%) cases followed by tobacco chewing. Clinically the most common complaint was cough in 65 (62.5%) cases, followed by weight loss. 10 cases were diagnosed as benign and 94 cases as malignant. Among benign lesions most common lung lesions were non-specific inflammatory lesions reported in 6 (5.77%) cases followed by granulomatous lesion in 3 (2.89%), hydatid cyst in 2 (1.93%) and aspergilloma in 1 (0.97%) case. Adenocarcinoma was the most common malignant lung lesion found in 52 (50%) cases followed by Squamous cell carcinoma 20 (24%), Small cell carcinoma 12 (13.04%) and Poorly differentiated carcinoma 6 (5.77%) cases. The sensitivity, specificity, positive predictive value, negative predictive value and accuracy of our study was 97.83%, 66.67%, 95.74%, 80.0% and 94.23% respectively. Conclusion: Guided FNAC and biopsy are safe, simple, less invasive, cost effective, well accepted and accurate diagnostic procedures with minimal complications and low morbidity rates.

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Comparative study of computed tomography guided fine needle aspiration cytology and trucut biopsy in diagnosis of lung cancer: a report of 81 cases

Cited by 3 publications

References 9 publications

Yield of Computed Tomography Guided Fine Needle Aspiration in Diagnosis of Suspected Cases of Lung Cancer: Experience of a Tertiary Care Hospital of North India

Yield of Computed Tomography Guided Fine Needle Aspiration in Diagnosis of Suspected Cases of Lung Cancer: Experience of a Tertiary Care Hospital of North India

The diagnostic utility of squash smear cytology in lung malignancies

A Study of Histocytological Findings of Lung Lesions in Image Guided Fnac and Biopsy in Tertiary Care Centre

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