Considering the worldwide growing prevalence of CKD and increasing importance of HRQoL in chronic diseases, improving our knowledge about HRQoL and its predictors in CKD patients is important. Assessment of HRQoL early in disease course will help to identify high risk patients in whom modifying these factors may help them lead an active and healthy life.
BACKGROUND:During the last few decades, high-resolution computed tomography (HRCT) has come up as a new diagnostic modality to diagnose emphysematous and chronic bronchitis components of chronic obstructive pulmonary disease (COPD). The present study was undertaken to evaluate for various quantitative and qualitative HRCT features in patients with COPD, and to detect patients' characteristics that correlate with these HRCT features.MATERIALS AND METHODS:Forty male patients with COPD attending the COPD clinic at a tertiary referral hospital and postgraduate medical institute were included in the study. Various HRCT features, including tracheal index, thoracic cage ratio, sterno-aortic distance, thoracic cross-sectional area, vascular attenuation, vascular distortion, mosaic attenuation pattern, and directly visible small airways, were evaluated and correlated with patients' characteristics, including age, duration of illness, quantum of smoking, dyspnea score, quality-of-life index, and various spirometric indices.RESULTS:We found significant correlations of various quantitative and qualitative HRCT features with age, duration of illness, quantum of smoking, quality-of-life index, and the spirometric indices showing the extent of airways obstruction.CONCLUSIONS:Various quantitative and qualitative HRCT features were found to correlate with patients' characteristics, spirometric indices, and health-related quality-of-life score, suggesting that HRCT is useful not only in detecting emphysema and its various subtypes but also in predicting the extent and severity of COPD.
summaryWe report a case of 19 year-old female patient diagnosed as systemic lupus erythematosus (SLE) presented with fever and diffuse cutaneous lesions. During the hospital stay she had acute pneumonia, pleural effusion and respiratory failure, which required intensive care unit (ICU) care and mechanical ventilator support. A fulminant course of the disease, decreased values of complement levels and positive antinuclear antibodies (ANA) in pleural fluid and repeated negative sputum for acid-fast bacillus, blood cultures enabled diagnosis of fulminant lupus pneumonitis. Fulminant lupus pneumonitis is a rare but potentially life threatening complication of SLE. Management requires involvement of multiple specialties and rigorous efforts in reviving the patient.
Backgound: In paediatric emergencies acute poisoning is frequently encountered and is the leading cause of morbidity and mortality in developing countries. There is natural division of acute poisoning in paediatric population in to two groups i.e. young children and adolescents. The first group comprises of young children who innocently ingest small amount of single substances. Second group comprises of adolescents who purposefully ingest substantial quantity of multiple substances secondary to emotional outburst or psychiatric illness. This study aimed to study the clinical, toxicological profile and outcome of Acute poisoning in paediatric population in Adichunchanagiri institute of medical sciences, Mandya, Karnataka, India. Subjects and methods: This is a retrospective observational study done from January 2018- December 2019, in Adichunchanagiri institute of medical sciences, Mandya, Karnataka, India, involving childhood poisoning. Data was noted on a predesigned proforma, it was compiled and entered in MS Excel spread sheet; descriptive statistics was applied. Results: Out of 50 cases 24 cases (48%) were males and 26 cases (52%) were females. Majority of cases were distributed in the age group of 1-4 years 24 cases (48%), followed by 15-18 years 19 cases (38%). Suicidal poisoning was more seen in adolescent females 15 cases (30%). Pesticide and insecticide remains the most common toxic agent i.e. 21 cases (42%), followed by hydrocarbons 16 cases (32%). 42 cases (84%) got improved, 5 cases (10%) got referred and there was 1 (2%) death. Majority of the cases (52%) got discharged between 1-3 days. Conclusions: Pesticides and hydrocarbons remains most easily accessible toxins in rural area hence, are most commonly implicated toxins in childhood poisoning. Though poisoning remains worrisome problem, it is preventable.
Background: A study of habit of fast food eating among school going adolescents and parental advice and its relation with their nutritional status. Methods: Design: an epidemiological analytic observational study. Subjects: 600 adolescents' 15-19 years of age, studying in 11 and 12 classes and included both boys and girls. A single observer interviewed each student and gathered the information regarding their eating habits. It was recorded on a pre-tested open and closed ended Performa. Nutritional status was assessed by BMI. The adolescents for the purpose of analysis were broadly grouped in two groups. Group I (those having normal BMI ranging 18.5 to 25) and group II (Malnourished i.e. those having BMI <18.5 to >25). Group II adolescents were further divided into group IIa (Underweight, BMI<18.5) and group IIb is (Over weight and obese BMI >25). Results: Adolescents who took both fast food and soft drinks 73.1% were malnourished (group II) as compared to those who did not take both the things 13.7% in group II. Difference was found to be statistically significant (p value <0.01). Out of 73.1% who took both fast food and soft drinks 62.1% and 11.0% were in group IIa (Underweight, BMI <18.5) and group IIb (Over weight and obese BMI >25) subsequently. Incidence of malnutrition was significantly less in 12.4% adolescents' interfered by their parents as compared to 69.6% of those where parents was not interfering. Difference was found to be statistically significant (P value <0.01). Conclusion: A habit of fast food eating and taking soft drink provokes malnutrition. Interference in eating by parents is beneficial among adolescents.
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