Comparative metabolic profiling of essential oils from Spondias pinnata (Linn. F.) Kurz and characterization of their antibacterial activities

Sameh, Salma; Al‐Sayed, Eman; Labib, Rola M.; Singab, Abdel Nasser B.

doi:10.1016/j.indcrop.2019.05.060

Cited by 25 publications

(14 citation statements)

References 20 publications

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“…Moreover, the carbonized ethanol extracts of E. rheedii , S. pinnata , S. rarak and T. grandis had greater activity against the Gram-positive bacteria compared to P. aeruginosa . Similar results have been reported by Sameh et al, 2019 [ 26 ] who reported that the essential oil from S. pinnata was highly active against MRSA and S. aureus . This oil contains sesquiterpenes, β-caryophyllene, oxygenated monoterpenes and α-terpineol are the main constituent and it is noteworthy that β-caryophyllene has been shown to have potent activity against S. aureus , P. aeruginosa with MICs of 3 ± 0.4 and 7 ± 1.2 μM [ 27 ]; α-terpineol also has anti- S. pyogenes activity [ 28 ].…”

Section: Discussionsupporting

confidence: 91%

Antibacterial, anti-inflammatory and antioxidant activities of Mahanintangtong and its constituent herbs, a formula used in Thai traditional medicine for treating pharyngitis

Dechayont

Phuaklee

Chunthorng-Orn

et al. 2021

BMC Complement Med Ther

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Background Mahanintangtong is listed in the Thailand’s National List of Essential Medicines (NLEM). It is used to treat non-specific fevers and illnesses such as pharyngitis and chickenpox. In this study, we investigated the biological activities of the different medicinal plants used in the Mahanintangtong formula. Methods The plant materials were extracted by maceration and decoction. Antimicrobial activity, assessed by disc diffusion method, the minimum inhibitory concentration (MIC), and minimum bactericidal concentration (MBC) were compared with commercially available standard antibiotics. To elucidate the anti-inflammatory mechanisms, inhibition of nitric oxide (NO), tumor necrosis factor α (TNF-α), and interleukin 6 (IL-6) production was tested by Griess and ELISA techniques. Antioxidant activity was measured by ABTS and DPPH scavenging assays. Results The extracts with the best antimicrobial activities were carbonized Tectona grandis showing against Streptococcus pyogenes, Staphylococcus aureus, Methicillin-resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa. The ethanol extract of Dracaena loureiroi wood exhibited the highest NO and IL-6 inhibitory activity with IC50 values of 9.42 ± 1.81 and 12.02 ± 0.30 μg/mL, respectively. The ethanol extract of Pogostemon cablin had the highest TNF-α inhibitory with IC50 values of 10.68 ± 0.02 μg/mL. In anti-free radical testing, the ethanol extract of D. loureiroi displayed high antioxidant activity by both ABTS and DPPH assays. Conclusion The ethanol extracts from carbonized T. grandis and Mahanintangtong showed good antimicrobial activity, especially against S. pyogenes, and good anti-inflammatory activity. These findings are relevant to the pathogenesis of pharyngitis and justify additional studies to see if Mahanintangtong could have clinical utility.

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Section: Discussionsupporting

confidence: 91%

Antibacterial, anti-inflammatory and antioxidant activities of Mahanintangtong and its constituent herbs, a formula used in Thai traditional medicine for treating pharyngitis

Dechayont

Phuaklee

Chunthorng-Orn

et al. 2021

BMC Complement Med Ther

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“…Experimental evidence have revealed that crude essential oils exhibit higher antimicrobial activity than their individual components possibly due to synergistic interactions between them 31 . Therefore, the crude oils are usually used in various medicinal and food applications as antimicrobial agents rather than their individual components 32 . However, previous studies have demonstrated that the anti‐ H. pylori activity of essential oils may be attributed to the presence of certain terpenoid compounds in the essential oils.…”

Section: Resultsmentioning

confidence: 99%

Phytochemical discrimination of Pinus species based on GC–MS and ATR‐IR analyses and their impact on Helicobacter pylori

Gad

Al‐Sayed

Ayoub

2021

Phytochemical Analysis

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Introduction The leaves and cones of Pinus plants as well as their essential oils have been used in traditional medicine for the treatment of several ailments. Objectives Phytochemical discrimination of Pinus species and investigation of their anti‐Helicobacter pylori activity in vitro and in silico. Materials and Methods Gas chromatography–mass spectrometry (GC–MS) and attenuated total reflectance infrared (ATR‐IR) metabolic profiling of the essential oils of Pinus species. Principal component analysis (PCA) and hierarchal cluster analysis (HCA) were applied for discrimination and segregation of Pinus species. Results GC–MS revealed the presence of 76 constituents, where monoterpenes represented the major class with the dominance of α‐pinene (72%) followed by β‐pinene (16%) for P. canariensis. β‐Pinene was the dominant component in P. pinea (24%) followed by terpinolene (11%). α‐Pinene (17%) and caryophyllene (12%) were the major components in P. halepensis, while, 3‐carene (33%) and α‐pinene (17%) represented the major constituents of P. roxburghii oil. By applying PCA and HCA on GC–MS and ATR‐IR data analysis, ATR‐IR displayed much better discrimination for Pinus species. The pine oils showed promising inhibitory effects on Helicobacter pylori. Furthermore, in silico molecular modelling was carried out where the calculated free binding energies of phytochemicals identified ranged from −33.71 to −19.67 kcal/mol for urease and −41.18 to −16.57 kcal/mol for shikimate kinase. This suggests favourable binding of pine essential oil components to both enzymes, thus explaining their potential inhibitory activity on H. pylori. Conclusion GC–MS and ATR‐IR based metabolic analyses could discriminate between Pinus species. Pine essential oils can be used as promising therapeutic drugs to protect against H. pylori infection.

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“…Salma et al, 63 reported that the GC / MS technique analysed essential oils obtained from the S. pinnata leaves, flower and fruits. Sesquiterpenes hydrocarbons were the predominant constituents in the leaf and flower essential oils (57.7% and 61.2), followed by oxygenated monoterpenes (30.4% and 28.8%).…”

Section: Phytochemistrymentioning

confidence: 99%

A Tangy Twist Review on Hog-Plum: Spondias pinnata (L.f.) Kurz

Mondal

Bhar²,

Panigrahi

et al. 2021

JNR

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Spondias pinnata (L.f.) Kurz., belongs to the Anacardiaceae family, generally referred to as Indian Hog plum, a deciduous, glabrous tree with a healthy fruit to eat. Hog plum is a mild deciduous tree plant of high nutritional value, stubby calories and abundant in vegetable proteins, zinc, chitin, starch, vitamins and minerals. Traditional use of various parts of S. pinnata includes diarrhea, dysentery, stomach troubles, hyperacidity, wounds, sprain, rheumatism, gonorrhoea, tuberculosis, aphrodisiac, arrow poison antidote, dyspepsia, dysentery, ring worms, abscess painful joints, refrigerant, tonic, antiseptic, astringent, mental disorders, tuberculosis, vomiting and many more. A number of pharmacological activities were reported from several extracts of S. pinnata and its parts that include hypoglycemic, anti-cancer, ulcer-protective, antidiarrhoeal, anti-microbial, hepatoprotective, thrombolytic, anti-inflammatory, antiarthritic, analgesic, antipyretic, antihypertensive, anthelmintic, diuretic and laxative, anti-tuberculosis, cytotoxic, antioxidant, anti-hyperlipidemic, ischemia reperfusion injury and preconditioning of heart, anxiolytic, reduce side effects of chemotherapy, ameliorating, platelet aggregation inhibitory activity and acute and sub-chronic toxicity. A few phytochemicals were detailed on this plant. The chemical components of S. pinnata include different amino acids, carbohydrates, terpenoids, flavonoids, polysaccharides, steroids and so on. Various solvent extract and their gas chromatography-mass spectrometry analysis have confirmed the structures of a number of important phytoconstituents. Hence this review can be a good reference for researchers who would undertake further investigation about S. pinnata.

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Comparative metabolic profiling of essential oils from Spondias pinnata (Linn. F.) Kurz and characterization of their antibacterial activities

Cited by 25 publications

References 20 publications

Antibacterial, anti-inflammatory and antioxidant activities of Mahanintangtong and its constituent herbs, a formula used in Thai traditional medicine for treating pharyngitis

Antibacterial, anti-inflammatory and antioxidant activities of Mahanintangtong and its constituent herbs, a formula used in Thai traditional medicine for treating pharyngitis

Phytochemical discrimination of Pinus species based on GC–MS and ATR‐IR analyses and their impact on Helicobacter pylori

A Tangy Twist Review on Hog-Plum: <i>Spondias pinnata</i> (L.f.) Kurz

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