Comparative Evaluation of Dental Implant Failure among Healthy and Well-Controlled Diabetic Patients—A 3-Year Retrospective Study

Abstract

Diabetes mellitus is known to compromise the various aspects of homeostasis, including the immune response and the composition of oral microflora. One of the oral manifestations of diabetes mellitus is tooth loss and the survival rate of dental implants chosen as a treatment modality for its rehabilitation is controversial. The current study aims to evaluate and compare the failure rate of dental implants between well-controlled diabetic and healthy patients. A retrospective study of case-control design was conceptualized with 121 well-controlled diabetic and 136 healthy individuals. Records of subjects who had undergone oral rehabilitation with dental implants between the periods of January 2013 to January 2016 were retrieved. Post-operative evaluation was carried out for all patients for about three years to assess the immediate and long-term success of the procedure. From a total of 742 dental implants, 377 were placed in well-controlled diabetic patients (case group) and 365 in healthy subjects (control group). A comparable (9.81%), but non-significant (p = 0.422) failure rate was found in the case group in comparison to the control group (9.04%). A non-significant (p = 0.392) raised number (4.98%) of failure cases were reported among females in comparison to males (4.44%). In respect to arch, the mandibular posterior region was reported as the highest failure cases (3.09%; p = 0.411), with 2.29% of cases reported in the mandibular anterior (p = 0.430) and maxillary posterior (p = 0.983) each. The maxillary anterior region was found to have the least number (1.75%; p = 0.999) of failure cases. More (4.98%; p = 0.361) cases were reported to fail during the functional loading stage in contrast to osseointegration (4.44%; p = 0.365). A well-controlled diabetic status does not impose any additional risk for individuals undergoing dental implant therapy.

Effect of Aqueous Ozone Solution Irrigation on Healing after Treatment with Dental Implants: A Cross-over Randomized Controlled Clinical Trial

“…Dental implants have provided advanced restorative solutions for tooth loss; however implantation should be performed meticulously to prevent the various complications that may accompany this procedure 1,2) . The early postoperative period is particularly important and invariably depends on soft tissue healing at the surgical site 3) . Therefore, certain materials may be utilized to increase the success rate of implant survival.…”

Should Quality of Glycemic Control Guide Dental Implant Therapy in Patients with Diabetes? Focus on: Peri-Implant Diseases

“…Although emerging evidence from a number of systematic reviews and meta-analyses suggest that chronic hyperglycemia is an important risk factor for peri-implant diseases, 23,30,31 however more recent lines of evidence do not indicate any significant association between diabetes and peri-implantitis. 6,32,33 Several recent metaanalyses have shown that diabetes and in particular poor glycemic control significantly correlates with predisposition and development of peri-implantitis. 23,30,31 A recent meta-analysis found that compared to non-diabetics, twice as many patients with diabetes were at risk of periimplantitis and that higher glycemic levels (HbA1c >8%) were associated with greater prevalence of peri-implant diseases.…”

“…31 However, other more recent studies have not found a similar trend between diabetes and peri-implantitis compared to metabolically healthy individuals. 6,32,33 While two studies only looked at patients with well-controlled diabetes, 6,32,33 in another independent study the male patients with poorly-controlled diabetes (HbA1c >8%) showed elevated peri-implant clinical and radiographic markers independent of periimplantitis. 6 Collectively, these studies emphasize the need for further well-controlled and long-term trials that compare patients with different glycemic profiles using consistent definitions as well as outcome indicators which can then be translated to appropriate management during implant therapy.…”

A Study of Creatinine Level among Patients with Dyslipidemia and Type 2 Diabetes Mellitus Using Multilayer Perceptron and Multiple Linear Regression

“…The compromised immune state may bring limitations to treatment planning for oral and systemic aliments. [ 1 ] Dyslipidemia is one of the major risk factors for coronary heart disease with diabetes mellitus. Diabetic dyslipidemia is associated with decreased high-density lipoprotein cholesterol concentrations, high plasma triglyceride concentrations, and increased concentrations of dense small low-density lipoprotein (LDL) cholesterol particles.…”