Comparative Effects of Scorpion Venom and Aqueous Basil (Ocimum basilicum) Leaves Extracts on Ccl4-induced Toxicity in Albino Rats

Salman, Muhammad; Kasem, Naglaa R. A.; Saleh, Nora Hm

doi:10.4172/2167-0889.1000201

Cited by 2 publications

(1 citation statement)

References 35 publications

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“…It appears from results that lion's foot was safe on renal functions. These data were adapted by [34] they found that reduction in serum uric acid level may be attributed to the increased utilization of uric acid against increased production of the free radical since it has a capable especially of reacting with free radicals.…”

Section: Data Inmentioning

confidence: 99%

Effect of Lion’s Foot (Alchemilla vulgaris) on Liver and Renal Functions in Rats Induced by CCl4

El-Hadidy¹,

Refat²,

Halaby³

et al. 2018

FNS

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The present work aims to study the influence of antioxidants activity of lion's foot (Alchemilla vulgaris) leaves at different concentrations to give more protection against chronic liver disease. Results indicated that dried lion's foot leaves had rich in total polyphenolic and flavonoids content (395.65 and 183.10 mg/100g, respectively). These results were reflected to the antioxidant activity (DPPH); it's noticed that the antioxidant activity of dried lion's foot leaves was high (131.74%). The major polyphenolic components were benzoic acid (1084.63 ppm) followed by ellagic acid, catechol, and catechin (614.16, 580.54, and 566.53 ppm, respectively) then salicylic acid and protocatechuic acid (479.71 and 444.43 ppm, respectively). On the same trend, flavonoids fractions indicated the highest content in luteo-6-arabinase 8-glucose, apig. 6-rhamnase 8-glucose, acatein, narengin and luteolin (40.01; 15.04; 8.07; 6.64 and 6.42 ppm, respectively). Fifty-six male albino rats were used in biological experiments. Rats fed on basal diet for two weeks before the performance of the experiment. At the beginning, rats divided into eight main group were fed on diets for 45 days as follows: Negative control group (first group) was fed on basal diet. Forty nine rats were fed on basal diet and induced by CCl 4 , in paraffin oil (50% v/v, 2 ml/Kg) twice weeks subcutaneous injection to induce chronic damage in the liver, then divided into 7 groups numbered from group 2 to group 8. Positive control group rats fed on basal diet till final experiment (second group). Group 3 and 4 rats treated with 50 and 100 ppm ethanolic leaves extracts, respectively. Also, group 5 and 6 treated with 50 and 100 ppm aqueous leaves extracts, respectively. All extracts were fed on orally every day. While, rats in group 7 treated with 1% and 2% dried lion's foot leaves. At the end of the experimental period, serums were collected to determine liver and

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Section: Data Inmentioning

confidence: 99%

Effect of Lion’s Foot (Alchemilla vulgaris) on Liver and Renal Functions in Rats Induced by CCl4

El-Hadidy¹,

Refat²,

Halaby³

et al. 2018

FNS

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Effects of Green Silver Nanoparticles on CCl4 Injured Albino Rats’ Liver

et al. 2019

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Comparative Effects of Scorpion Venom and Aqueous Basil (Ocimum basilicum) Leaves Extracts on Ccl4-induced Toxicity in Albino Rats

Cited by 2 publications

References 35 publications

Effect of Lion’s Foot (<i>Alchemilla vulgaris</i>) on Liver and Renal Functions in Rats Induced by CCl<sub>4</sub>

Effect of Lion’s Foot (<i>Alchemilla vulgaris</i>) on Liver and Renal Functions in Rats Induced by CCl<sub>4</sub>

Effects of Green Silver Nanoparticles on CCl4 Injured Albino Rats’ Liver

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Comparative Effects of Scorpion Venom and Aqueous Basil (Ocimum basilicum) Leaves Extracts on Ccl4-induced Toxicity in Albino Rats

Cited by 2 publications

References 35 publications

Effect of Lion’s Foot (&lt;i&gt;Alchemilla vulgaris&lt;/i&gt;) on Liver and Renal Functions in Rats Induced by CCl&lt;sub&gt;4&lt;/sub&gt;

Effect of Lion’s Foot (&lt;i&gt;Alchemilla vulgaris&lt;/i&gt;) on Liver and Renal Functions in Rats Induced by CCl&lt;sub&gt;4&lt;/sub&gt;

Effects of Green Silver Nanoparticles on CCl4 Injured Albino Rats’ Liver

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Effect of Lion’s Foot (<i>Alchemilla vulgaris</i>) on Liver and Renal Functions in Rats Induced by CCl<sub>4</sub>

Effect of Lion’s Foot (<i>Alchemilla vulgaris</i>) on Liver and Renal Functions in Rats Induced by CCl<sub>4</sub>