Combined magnification endoscopy with chromoendoscopy for the evaluation of Barrett's esophagus

Advanced Imaging in Barrett's Esophagus

“…The first use of magnification endoscopy in BE was described in 1994 in which Lugol solution and indigo carmine were used to identify a villiform surface mucosal pattern, which correlated with histologic intestinal metaplasia. 9 Subsequent studies have similarly used indigo carmine or methylene blue with high-magnification endoscopy for identification of BE and surveillance of dysplasia and neoplasia. [10][11][12] NBI has also been combined with high-resolution magnification endoscopy in the management of BE.…”

“…Indigo carmine was used in the first successful demonstration of dye-based chromoendoscopy in the evaluation of BE. 9 Indigo carmine is unique in that the dye is not absorbed by the epithelium. Rather, the solution settles between the pits and grooves of the surface epithelium, providing a detailed topographic image of the mucosa.…”

Magnifying endoscopy in the diagnosis of Barrett's esophagus and Barrett's adenocarcinoma

“…These efforts have led to the various systems for the classifi cation of mucosal surface patterns. One of the simplest procedures that combine magnifying endoscopy with chromoendoscopy is indigo carmine dye by the contrast technique [13]. Methylene blue dye [5] and 0.05% crystal violet dye [10,14] can also be used to stain the columnar surface epithelium.…”

Zoom endoscopic monitoring of small bowel allograft rejection

“…The use of magnification endoscopy has been reported for evaluation of BarrettÕs esophagus and celiac disease [25,28]. Subsequently, in 1999, we published the first case report featuring magnification with a zoom video endoscope (ZVE) for evaluation of intestinal graft mucosa [16].…”