Colorimetric Receptors for the Detection of Biologically Important Anions and Their Application in Designing Molecular Logic Gate

Abstract

Three new colorimetric receptors were synthesised for the detection of biologically important anions such as fluoride and acetate in the aqueous medium. All receptors showed significant colour change for F À and AcO À ions. The synthesised receptors were characterized by spectroscopic methods such as NMR techniques for structural confirmation. The UV-vis and 1 H NMR titrations were performed to understand the binding mechanism of the receptors with F À and AcO À ions. Further, Job's plot was used to explore the stoichiometry between receptor and analyte. Besides, the visual and spectroscopic changes of receptor R1 upon the addition of F À ion was utilised to study the reversible behaviour by adding Cr 3 + ions. This concept was explored to mimic the logic gates at the molecular level with "set-reset" Boolean operations as a proof of concept.

Advances in Applications of Molecular Logic Gates

“…Both F – ions and AcO – ions are important anions in aqueous media . F – ion is related to human health problems.…”

“…It can also be used in hemodialysis. Excessive intake of AcO – ion in the human or animal body will affect the metabolism of the organism . Fe 3+ ion plays an important role in cell metabolism and oxygen transport in the life system.…”

“…Both F − ions and AcO − ions are important anions in aqueous media. 6 F − ion is related to human health problems. As a drug ingredient, it can be used for sleeping pills, anesthetics, etc., and in clinical medicine, it can also be used for tooth etc., and can even lead to cancer in serious cases.…”

“…Excessive intake of AcO − ion in the human or animal body will affect the metabolism of the organism. 6 Fe 3+ ion plays an important role in cell metabolism and oxygen transport in the life system. An Fe 3+ ion content different from the normal value will lead to anemia and other diseases.…”

Recent Advances in Microfluidic Platform for Physical and Immunological Detection and Capture of Circulating Tumor Cells

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