Colorimetric detection of kanamycin based on analyte-protected silver nanoparticles and aptamer-selective sensing mechanism

Nanomaterial based aptasensors for clinical and environmental diagnostic applications

“…Silver nanoparticles (AgNPs) are second to AuNPs in their applicability in colorimetric assays, which are usually based on the turning-off or turning-on of the signal. [62][63][64] AgNPs lack the colour switching property and consequently the ability of usage in signal-switch type sensors. Other metal-based nanoparticles like copper nanoparticles (CuNPs), iron nanoparticles (FeNPs), and platinum nanoparticles (PtNPs) are less exploited in colorimetric assays as transducers but rather explored for other properties like catalysis or magnetism.…”

Aptamer-based Biosensors for Antibiotic Detection: A Review

“…Regarding to higher extinction coefficients of silver nanoparticles (AgNPs) than AuNPs, Xu et al created a colorimetric aptasensor for kanamycin detection based on unmodified AgNPs [75]. The saltinduced aggregation of the AgNPs is protected in the presence of amino-functionalized kanamycin due to their adsorption onto AgNPs surface via Ag-N binding and steric stabilization.…”

Staphylococcus aureus detection in blood samples by silica nanoparticle-oligonucleotides conjugates

“…We developed previously a magnetic pre-concentration of microorganisms for Salmonella detection from milk samples by PCR, real-time PCR (rtPCR) and quartz Crystal Microbalance (QCM) Ozalp et al 2015b;Ozalp et al 2014). Later, similar strategies were adapted by other research groups (Eslami and Alizadeh 2015;Xu et al 2015). Bloodstream infections are life-threatening condition, that can lead to septic shocks.…”