Colloidal HPMO Nanoparticles: Silica‐Etching Chemistry Tailoring, Topological Transformation, and Nano‐Biomedical Applications

Abstract

Hybridization produces the better: Colloidal hollow periodic mesoporous organosilica nanoparticles (HPMO NPs) with tunable compositions and highly hybridized nanostructures are successfully synthesized by a simple, easily scale-up but versatile silica-etching chemistry (alkaline or HF etching) for their applications in nano-fabrication and nano-medicine.

Facile Synthesis of Yolk–Shell Structured Inorganic–Organic Hybrid Spheres with Ordered Radial Mesochannels

“…It is reported that the integration of organic and inorganic fragments can endow the obtained hybrid materials with mechanical stability, hydrothermal stability, tailored surface polarities, and even good biocompatibility for different applications, such as catalysis, energy conversion, drug delivery, and so on. [34][35][36][37][38] However, to the best of our knowledge, there is no report about synthesizing yolk-shell spheres in which the core and shell are made of inorganic-organic hybrid material. Overall, it remains a grand challenge to fabricate monodisperse yolk-shell structures with tunable size, accessible ordered mesochannels, inorganicorganic hybrid framework by a facile approach.…”

Mesoporous carbon biomaterials

“…Toward addressing these concerns, we recently developed a new in situ framework transformation strategy to synthesize hollow MCNs (HMCNs) with large hollow interiors and unique red blood cell (RBC) morphology [48]. Mesoporous organosilica nanoparticles (MONs) were initially synthesized with benzene-bridged organic-inorganic hybrid frameworks [49]. High-temperature calcination of mesoporous organosilica carbonizes the organic-benzene groups to form a mesoporous carbon framework within the silica framework.…”

Colloidal Mesoporous Silica Nanoparticles

“…HF caused the etching of the interface between the solid silica core and organosiloxane shell. 160 Therefore, rattle-like structures were obtained. Although this method is quite useful, the template removal process tends to generate by-products and destroy the structure.…”

“…Accordingly, various hollow MSNs have been prepared by using versatile templates which can be categorized as soft and hard templates. 160,161,175,179285 In particular, we will describe on the colloidal dispersity of those MSNs (Figure 19). …”