Collapse, shrinkage and structural changes in dried alginate gels containing fillers

Rassis, Dorit; Saguy, I. Sam; Nussinovitch, A.

doi:10.1016/s0268-005x(01)00071-6

Cited by 71 publications

(32 citation statements)

References 17 publications

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“…Starch addition consistently increased the stiffness of the gum karaya patch and as a result, its resistance to deformation. This is not all that surprising and in fact, has already been observed in other systems, e.g., inclusion of fillers in dried alginate gels (36) or in microcapsules for drug delivery. In the latter, filler inclusion contributed to the stability of the carriers and prolonged the time of drug release by 6.5-8.5 h relative to carriers that contained no filler (37).…”

Section: Compression Testsupporting

confidence: 71%

Physical Properties of Gum Karaya-Starch-Essential Oil Patches

2010

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Abstract. Essential oils are used in foods, cosmetics, and pharmaceuticals. Despite the recent marketing of novel essential-oil-containing patches, there is no information on their production, constituents, or physical properties. The objectives of this study were to produce essential-oil patches and characterize their physical properties. The essential oil of Lavandula angustifolia (lavender) was included at concentrations of 2.5% to 10% in patches manufactured from the exudate gum karaya, propylene glycol, glycerol, emulsifier, and optionally, potato starch as filler. Inclusion of essential oil reduced patch strength, stiffness, and elasticity relative to patches without essential oil. Inclusion of starch in the essential-oil patches strengthened them, but reduced their elasticity. Patches' adhesion to substrate was examined by both peeling and probe-tack tests: the higher the inclusion of essential oils within the patch, the larger the decrease in its adhesion to substrate. Addition of starch to essential-oil-containing patches increased their adhesion relative to their essential-oil-only counterparts. Scanning electron micrographs of the patches provided evidence of entrapped starch granules. Although inclusion of essential oil reduced both the mechanical properties and adhesion of the patches, a high proportion of essential oil can still be included without losing patch integrity or eliminating its adhesiveness to the skin.

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Section: Compression Testsupporting

confidence: 71%

Physical Properties of Gum Karaya-Starch-Essential Oil Patches

2010

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“…According to Kamaruddin et al [18] during formation of capsules at higher concentrations of alginate and cross-linking agent, a stiff gel is quickly generated which can promote the release of encapsulated material from the core. e inclusion of 2% (w/w) of inulin in all treatments increased the encapsulation efficiency by the reduction of pore size of alginate beads in the presence of the filler (inulin), which prevented the leakage of the encapsulated compounds [19]. With treatment 2, the encapsulation efficiency was high for both phenolic compounds and steviol glycosides, simultaneously.…”

Section: Encapsulation Efficiencymentioning

confidence: 95%

Release Kinetic Studies of Stevia rebaudiana Extract Capsules from Sodium Alginate and Inulin by Ionotropic Gelation

Martínez

Ruiz

Campos

2018

Advances in Materials Science and Engineering

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is study was oriented towards encapsulation of S. rebaudiana extract and the study of its release kinetics. e desired encapsulation was achieved by the ionotropic gelation method using sodium alginate and inulin of polymeric constituents. Characterization of the capsules was performed by micrometric properties, encapsulation efficiency, in vitro extract release analysis, and biological activity of released extract. e in vitro release profiles from different capsules were applied on different kinetic models. e prepared capsules were found spherical in shape with diameters ranging from 2.07 to 2.63 mm, having the encapsulation efficiencies of 43.77% and 56.53% for phenolic compounds and steviol glycosides, respectively. e best-fit model with the highest correlation coefficient was observed in the Ritger-Peppas model, indicating diffusion controlled principle. e release exponent n value obtained from the Korsmeyer-Peppas model varied between 0.2273 and 1.1719, confirming that the mechanism of S. rebaudiana extract bioactive compounds release was diffusion controlled.

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“…Also, inulin was investigated as a filler to improve the final properties of the alginate microbeads. Fillers are known to have the ability to induce structural changes in terms of influencing and increasing brittleness (i.e., creating a crunchier product) [46]. Specifically, alginate-inulin hydrogel has potential in food applications since inulin can be used as a functional food and as a source of dietary fibre.…”

Section: +mentioning

confidence: 99%

“…The results indicate that this type of microbead had the highest encapsulation capacity for this study. According to Rassis et al [46], fillers like inulin prevent the leakage of the encapsulated compounds. In the present study, 20% (mass with respect to the content of alginate) of inulin mass was added for each treatment.…”

Section: +mentioning

confidence: 99%