Cold crystallization of water in hydrated poly(2-methoxyethyl acrylate) (PMEA)

Tanaka, Masaru; Motomura, Tadahiro; Ishii, Naoki; Shimura, Kei; Onishi, Makoto; Mochizuki, Akira; Hatakeyama, Tatsuko

doi:10.1002/1097-0126(200012)49:12<1709::aid-pi601>3.0.co;2-l

Cited by 179 publications

(172 citation statements)

References 15 publications

(9 reference statements)

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“…These novel P-NCs (abbreviated as M-NCs), 11,73 which consist of hydrophobic poly(2-methoxyethyl acrylate) (PMEA) and hydrophilic inorganic clay (hectorite), have superior optical and mechanical properties, despite their high C clay , because of the unique organic/inorganic network structure composed of aggregated clay and PMEA. Here, PMEA is basically a hydrophobic polymer with a low T g (À341C), 74 and is considered to have promising applications in medical devices such as cardiopulmonary bypass, [75][76][77] although in practical applications PMEA has only been used as an ingredient of copolymers or as a thin coating because of its mechanical weakness and intractability. Further, it was found that M-NCs show thermoresponsible cell adhesion/detachment useful for a living cell harvest system.…”

Section: Other Characteristicsmentioning

confidence: 99%

Synthesis and properties of soft nanocomposite materials with novel organic/inorganic network structures

Haraguchi

2011

Polym J

211

167

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We have fabricated new types of polymer hydrogels and polymer nanocomposites, that is, nanocomposite gels (NC gels) and soft polymer nanocomposites (M-NCs), with novel organic/inorganic network structures. Both NC gels and M-NCs were synthesized by in situ free-radical polymerization in the presence of exfoliated clay platelets in aqueous systems and were obtained in various forms and sizes with a wide range of clay contents. Here, disk-like inorganic clay nanoparticles function as multifunctional crosslinkers to form new types of network systems. NC gels have extraordinary optical, mechanical and swelling/deswelling properties, as well as a number of new characteristics relating to optical anisotropy, polymer/clay morphology, biocompatibility, stimuli-sensitive surfaces, micropatterning and so on. The M-NCs also exhibit dramatic improvements in optical and mechanical properties including ultrahigh reversible extensibility and well-defined yielding behavior, despite their high clay contents. Thus, the serious disadvantages (intractability, mechanical fragility, optical turbidity, poor processing ability, low stimulus sensitivity and so on) associated with the conventional, chemically crosslinked polymeric materials were overcome in NC gels and M-NCs. Keywords: clay; hydrogel; mechanical properties; nanocomposite; network INTRODUCTIONPolymer nanocomposites (P-NCs), composed of organic polymer and inorganic nanoparticles, have been widely investigated in the last three decades to develop new, value-added polymeric materials based on existing polymers. [1][2][3][4] To date, many P-NCs consisting of various polymers and inorganic nanoparticles (for example, silica, silsesquioxane, titania, clay, carbon nanotubes) have been developed by using sol-gel reactions of metal alkoxides or organic premodification of nanoparticles. [1][2][3][4][5] The resulting P-NCs show significant improvements in some properties, such as modulus, heat-distortion temperature, hardness, gas impermeability and so on. However, the P-NCs developed so far have encountered inherent difficulties in preparation and processing as the inorganic content increases. In the case of polymer/ clay nanocomposites, in general, only a few weight percent of clay can actually be incorporated into NCs (o10 wt%, at the most) in the form of organic modified clay. 2,4,5 Further increases in clay content often cause structural inhomogeneities because of inadequate dispersion or irregular aggregation of the clay, and always result in disadvantageous optical and mechanical properties and processability.To overcome these limitations, we extend the concept of 'organic/ inorganic nanocomposites' to the field of soft materials, such as 'polymer hydrogels' and 'soft polymers,' under the strategy of fabricating novel organic/inorganic structures. In the present article, we give an overview of the development of two types of soft nanocomposites,

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Section: Other Characteristicsmentioning

confidence: 99%

Synthesis and properties of soft nanocomposite materials with novel organic/inorganic network structures

Haraguchi

2011

Polym J

211

167

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“…[16] Tanaka et al suggested that biocompatible materials such as poly(2-methoxyethyl acrylate) (PMEA) had a specific sorbed water, so-called ''cold-crystallization water''. [47] Recently, Hatakeyama et al reported that they could not observe the cold-crystallization phenomenon for a poly(MPC-ran-BMA) film which showed an excellent blood-compatibility. [48] Therefore, cold-crystallization may not be crucial for blood-compatibility.…”

Section: Complement Activation and Formation Of Tat Complexmentioning

confidence: 99%

Anti‐Biofouling Properties of Polymers with a Carboxybetaine Moiety

Tada¹,

Inaba²,

Mizukami³

et al. 2008

Macromolecular Bioscience

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The resistance of random copolymers of BMA and CMB against biofouling was evaluated. The amount of proteins adsorbed onto the CMB copolymers was smaller than that onto other polymers (non-ionic polymers and copolymers of ordinary ionic monomers and BMA) and decreased with an increase in the content of CMB residues. Furthermore, there was a dramatic decrease in the number of cells (platelets and fibroblasts) that adhered to the CMB copolymers compared with that to other polymers. In contrast with this, CMB copolymers were slightly perturbative to both complement and coagulation systems. However, the overall results suggest that zwitterionic moieties are effective for making polymer materials biocompatible due to their excellent anti-biofouling property.

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“…In a DSC study, a large exothermic peak due to the so-called cold crystallization is observed reproducibly in heating process, within a wide range of water content. 12 The water molecules showing the cold crystallization are considered to be weakly bound to high polymer chains, in the intermediate strength range between non-freezable water and free water. The phenomenon of cold crystallization is characteristic of biocompatible materials such as PEG, polysaccharides and gelatins, and is considered as the key point of achieving biocompatibility.…”

Section: Introductionmentioning

confidence: 99%

High Frequency Spectroscopic Study of the Bound State of Water in PEG-H2O System during Heating from Frozen State

Takei

Sugitani

2010

Anal. Sci.

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The bound state of water in PEG (polyethylene glycol)-H2O systems was studied by using HFS and DSC methods. Samples with the mixing ratios EO:H2O = 1:1 (a) and 1:10 (b), where EO indicates the ethylene oxide units in PEG chain, were heated from frozen state to melt state. Sample (a) gave an HFS peak corresponding to the weakly bound water, while sample (b) gave the peaks of both the bound and free water. DSC measurements gave quite similar patterns to those of HFS measurements, but with additional peaks corresponding to cold crystallization. The difference between the two measurements was reasonably interpreted by considering the origin of the cold crystallization.

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Cold crystallization of water in hydrated poly(2-methoxyethyl acrylate) (PMEA)

Cited by 179 publications

References 15 publications

Synthesis and properties of soft nanocomposite materials with novel organic/inorganic network structures

Synthesis and properties of soft nanocomposite materials with novel organic/inorganic network structures

Anti‐Biofouling Properties of Polymers with a Carboxybetaine Moiety

High Frequency Spectroscopic Study of the Bound State of Water in PEG-H2O System during Heating from Frozen State

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