Cognitive Changes in Comorbidity Alcohol Dependence and Affective Disorders

Галкин, С.А.; Пешковская, А. Г.; Kisel, N.I.; Васильева, С. Н.; Ivanova, Svetlana A.; Бохан, Н. А.

doi:10.30629/2618-6667-2020-18-3-42-48

Cited by 3 publications

(2 citation statements)

References 19 publications

(14 reference statements)

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“…One recent study revealed that patients with comorbid alcohol dependence and affective disorder manifested significant impairments in executive control, working memory, attention and cognitive flexibility compared to healthy individuals, and patients with only alcohol dependence or affective disorder [ 27 ].…”

Section: Discussionmentioning

confidence: 99%

“…BD patients with AUD show impaired verbal learning and memory [ 21 , 22 ], higher delay discounting [ 23 ], significant memory deficits more specifically the recognition of previously presented information [ 24 ] and, more deficits in executive functioning [ 25 , 26 ]. One study found significant impairments in executive control, working memory, attention and cognitive flexibility in comorbid AUD and BD patients, compared to healthy individuals, and patients with only AUD or BD patients [ 27 ]. On the other hand, BD patients without AUD also show impaired verbal learning and memory [ 21 , 22 ].…”

Section: Introductionmentioning

confidence: 99%

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Reaction Time and Visual Memory in Connection to Alcohol Use in Persons with Bipolar Disorder

et al. 2021

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The purpose of this study was to explore the association of cognition with hazardous drinking and alcohol-related disorder in persons with bipolar disorder (BD). The study population included 1268 persons from Finland with bipolar disorder. Alcohol use was assessed through hazardous drinking and alcohol-related disorder including alcohol use disorder (AUD). Hazardous drinking was screened with the Alcohol Use Disorders Identification Test for Consumption (AUDIT-C) screening tool. Alcohol-related disorder diagnoses were obtained from the national registrar data. Participants performed two computerized tasks from the Cambridge Automated Neuropsychological Test Battery (CANTAB) on A tablet computer: the 5-choice serial reaction time task, or reaction time (RT) test and the Paired Associative Learning (PAL) test. Depressive symptoms were assessed with the Mental Health Inventory with five items (MHI-5). However, no assessment of current manic symptoms was available. Association between RT-test and alcohol use was analyzed with log-linear regression, and eβ with 95% confidence intervals (CI) are reported. PAL first trial memory score was analyzed with linear regression, and β with 95% CI are reported. PAL total errors adjusted was analyzed with logistic regression and odds ratios (OR) with 95% CI are reported. After adjustment of age, education, housing status and depression, hazardous drinking was associated with lower median and less variable RT in females while AUD was associated with a poorer PAL test performance in terms of the total errors adjusted scores in females. Our findings of positive associations between alcohol use and cognition in persons with bipolar disorder are difficult to explain because of the methodological flaw of not being able to separately assess only participants in euthymic phase.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Reaction Time and Visual Memory in Connection to Alcohol Use in Persons with Bipolar Disorder

et al. 2021

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Cerebral hemodynamics and executive functioning in patients with alcohol use disorders

Галкин¹,

Tkacheva²,

Oshkina³

et al. 2022

Z. nevrol. psikhiatr. im. S.S. Korsakova

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Methodological Problems of Psychometric Tests in Clinical Studies of Cognitive Disorders in Patients with Cerebral Vascular Lesions: a Review

Aizenshtein

Trofimova

Mikadze

et al. 2023

Bulletin of Rehabilitation Medicine

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AIM. To assess cognitive dysfunction in clinical practice, depending on the task being solved in the examination, different neuropsychological research methods are used. To identify the specific cause of the dysfunctions in the structure of various mental functions (neuropsychological characteristics of the defect) and in the brain functions (topical diagnosis), methods of qualitative analysis of the detected symptoms of the disorder are used. Psychometric (quantitative) methods are used to assess numerically the severity of disorders and the dynamics of changes in the state of individual mental functions, as well as for screening assessment of e possible cognitive decline level in general. Methods of cognitive dysfunctions qualitative assessment are focused on the search for a «missing link» in the structure of the examined mental functions. Psychometric tests, in most cases, describe the general state of either individual mental functions, or, in the case of screening, a set of cognitive functions. Thus, one or more aspects of mental functions are evaluated, in which several cognitive functions are involved at once. The article presents the results of a literature review with a description and analysis of preferences, methods used and corresponding techniques for neuropsychological examination of cognitive disorders in domestic clinical practice in vascular brain lesions.

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Cognitive Changes in Comorbidity Alcohol Dependence and Affective Disorders

Cited by 3 publications

References 19 publications

Reaction Time and Visual Memory in Connection to Alcohol Use in Persons with Bipolar Disorder

Reaction Time and Visual Memory in Connection to Alcohol Use in Persons with Bipolar Disorder

Cerebral hemodynamics and executive functioning in patients with alcohol use disorders

Methodological Problems of Psychometric Tests in Clinical Studies of Cognitive Disorders in Patients with Cerebral Vascular Lesions: a Review

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