“…It is probable that RNA + peptide mutations are also important and required in avian hearing systems given that the calcium-activated potassium channel slowpoke (cSlo), which has hundreds of mutation variations and each of which is tuned to a distinct sound frequency, is [ 81 ]. Combinations of splicing, RNA, and peptide mutations may be useful for ultrasound detection in a number of organisms, including bats, dogs, dolphins, fish, and frogs [ 82 – 85 ]. For the ability to distinguish between hundreds of sounds and detect high- and low-frequency noises in quiet and complex noisy environment, RNA + peptide mutations may be crucial.…”