“…Other investigators have also demonstrated various ways of integrating light sources into silicon devices such as light-emitting diodes (LEDs) [22,23], organic LEDs (OLEDs) [24,25] and lasers [26]. A monolithic LED and complementary metal-oxide-semiconductor (CMOS) detection circuit has also been demonstrated [27], however no experimental results were provided. The absence of an optical filter is suspected for this omission.…”
Lab-on-a-chip (LOC) biological assays have the potential to fundamentally reform healthcare. The move away from centralized facilities to Point-of-Care (POC) testing of biological assays would improve the speed and accuracy of these, thereby improving patient care. Before LOC can be realized, a number of challenges must be addressed: the need for expert users must be abstracted away; the manufacturing cost of $5 per test threshold must be met; and the supporting infrastructure must be integrated down to an easily portable size. These challenges can be addressed with the deposition of microfluidics on CMOS chips. By designing application specific integrated circuits (ASICs) much of the automation and the supporting infrastructure needed to run these assays can be integrated into the chip. Additionally, CMOS fabrication is some of the most optimized manufacturing in industry today. My parents, thank you for providing me with food and shelter while in Alberta and never ending support while I was in Ontario. Keesa, my lovely fiance, without you I never would have gotten this far; probably not even close. Evelyn, your kitchen table debates over genetics and technology pushed me to discover new knowledge; endless appreciation.To my colleges at the U of A:
“…Other investigators have also demonstrated various ways of integrating light sources into silicon devices such as light-emitting diodes (LEDs) [22,23], organic LEDs (OLEDs) [24,25] and lasers [26]. A monolithic LED and complementary metal-oxide-semiconductor (CMOS) detection circuit has also been demonstrated [27], however no experimental results were provided. The absence of an optical filter is suspected for this omission.…”
Lab-on-a-chip (LOC) biological assays have the potential to fundamentally reform healthcare. The move away from centralized facilities to Point-of-Care (POC) testing of biological assays would improve the speed and accuracy of these, thereby improving patient care. Before LOC can be realized, a number of challenges must be addressed: the need for expert users must be abstracted away; the manufacturing cost of $5 per test threshold must be met; and the supporting infrastructure must be integrated down to an easily portable size. These challenges can be addressed with the deposition of microfluidics on CMOS chips. By designing application specific integrated circuits (ASICs) much of the automation and the supporting infrastructure needed to run these assays can be integrated into the chip. Additionally, CMOS fabrication is some of the most optimized manufacturing in industry today. My parents, thank you for providing me with food and shelter while in Alberta and never ending support while I was in Ontario. Keesa, my lovely fiance, without you I never would have gotten this far; probably not even close. Evelyn, your kitchen table debates over genetics and technology pushed me to discover new knowledge; endless appreciation.To my colleges at the U of A:
“…In addition, light emitted from a sharp tip does not have a large power output, despite the high intense emission in unit area. However, great interest in developing technologically viable, large scale silicon displays remains because of their high integration rate [27][28][29][30] and high density [31].…”
Research on design and firing performance of Si-based detonator Defence Technology 10, 34 (2014); A leakage current suppression technique for cascade SRAM array in 55 nm CMOS technology SCIENCE CHINA Information Sciences 57, 082405 (2014); GaN-on-Si laser diode: open up a new era of Si-based optical interconnections Science Bulletin 61, 1723 (2016); Study of LED array fill light based on parallel particle swarm optimization in greenhouse planting Information Processing in Agriculture 6, 73 (2019);. RESEARCH PAPER. SCIENCE CHINA Information Sciences
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