Cloning, characterization, and expression analysis of extracellular copper/zinc superoxide dismutase gene from bay scallop Argopecten irradians

Molecular characterization of a manganese superoxide dismutase and copper/zinc superoxide dismutase from the mussel Mytilus galloprovincialis

“…The transcripts of MnSOD and CuZnSOD were up-regulated to eliminate excessive ROS and protect the host against oxidative damage caused by bacterial stimulation. Similar expression profile was also found in bay scallop A. irradians, significant increase of MnSOD and extracellular CuZnSOD transcripts in hemocytes occurred at 3 h and 6 h post V. anguillarum challenge, respectively [13,14]. However, no significant change occurred in the intracellular CuZnSOD expression level of A. irradians in hemcoytes post V. anguillarum challenge [19].…”

“…expression level of MnSOD was speculated to be related with tissue-dependent mitochondrial content and oxidative load [23]. For CuZnSOD, the transcript was dominantly detected in gills of Chlamys farreri and A. irradians, whereas extracellular CuZnSOD of A. irradians and intracellular CuZnSOD of R. philippinarum transcripts were mainly detected in hemocytes [14,18,19,24]. The differences in the tissue-distribution of CuZnSOD expression may be attributed to the balance of various biological processes acting on the production of ROS in different environments [18].…”

“…At present, several SOD genes have been cloned in bivalves, including scallops [13,14,18,19], oysters [20,21] and clams [15,22e 24]. To our knowledge, there is no report about MnSOD gene in mussels including M. galloprovincialis.…”

The modulation of extracellular superoxide dismutase in the specifically enhanced cellular immune response against secondary challenge of Vibrio splendidus in Pacific oyster (Crassostrea gigas)

“…In bay scallop and Hong Kong oyster, the mRNA expression level of EcSOD increased post the challenges with microorganisms (Bao et al, 2009;Yu et al, 2011). Whereas a deduction of CgEcSOD mRNA in Pacific oyster was revealed one day post V. aestuarianus 01/32 stimulus (Labreuche et al, 2006).…”

“…The transcriptional expressions of EcSOD in mollusk after stimulation with foreign invaders were well studied previously, but the reported expression patterns were in controversy (Bao et al, 2009;Labreuche et al, 2006;Yu et al, 2011). In bay scallop and Hong Kong oyster, the mRNA expression level of EcSOD increased post the challenges with microorganisms (Bao et al, 2009;Yu et al, 2011).…”