Clinicopathological Analysis of Rhabdoid Meningiomas: Report of 12 Cases and a Systematic Review of the Literature

Zhou, Yu; Xie, Qing; Gong, Yi; Mao, Ying; Zhong, Ping; Che, Xiaoming; Jiang, Chengchuan; Fengping, Huang; Zheng, Kewen; Li, Shiqi; Gu, Yuxiang; Bao, Weimin; Yang, Baofeng; Wu, Jinsong; Wang, Yin; Chen, Hong; Xie, Lihui; Zheng, Mingzhe; Wang, Daijun; Zhu, Hongda; Chen, Xiancheng

doi:10.1016/j.wneu.2012.08.002

Cited by 21 publications

(22 citation statements)

References 37 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…RMs, which are classified as malignant meningioma (WHO grade III), comprise between 0.28% and 3.30% of meningiomas . The ratio of male‐to‐female incidence is 40:35, and the age distribution ranges from 2 to 84 years in previous reports with detailed data.…”

Section: Discussionmentioning

confidence: 98%

“…The ratio of male‐to‐female incidence is 40:35, and the age distribution ranges from 2 to 84 years in previous reports with detailed data. To date 110 cases of RM in 40 articles have been reported . The most common locations were convexity (25 of 74), anterior or middle cranial fossa (10 of 74), posterior cranial fossa (13 of 74) and falx or parasagittal sinus (16 of 74).…”

Section: Discussionmentioning

confidence: 99%

“…In 2000, RM was adopted as an aggressive variant of meningioma, designated as WHO grade III malignancy . The clinical course of RM is determined by local recurrences, invasion of adjacent brain and/or dura, widespread leptomeningeal dissemination, remote metastases and fatal clinical outcome . We report a rare case of RM with metaplastic, papillary and chordoid features.…”

Section: Introductionmentioning

confidence: 98%

See 2 more Smart Citations

Aggressive rhabdoid meningioma with osseous, papillary and chordoma‐like appearance

Karabağlı

Yavaş

2014

Neuropathology

View full text Add to dashboard Cite

Meningiomas are the most common primary intracranial tumors. They are usually benign and slowly growing; however, they may show histologically malignant features categorizing them into grade II or III of World Health Organization (WHO) classification. Rhabdoid meningioma (RM) is an uncommon meningioma variant categorized as WHO grade III. The clinical course of RM is determined by local recurrences, invasion of adjacent brain and/or dura, widespread leptomeningeal dissemination, remote metastases and fatal clinical outcome. Herein we report a case with recurrent aggressive left occipital parasagittal region RM in which the patient initially declined radiation treatment. The tumor was resected four times in 5 years. Histopathological examination revealed a rhabdoid meningioma with metaplastic, papillary and chordoid differentiation. Six months after her fourth operation the patient died of progressive disease. RM is a rare subtype of malignant meningioma and the role of different adjuvant therapeutic options are still unknown. Clinical presentation, radiological features and pathologic findings of this uncommon tumor are discussed.

show abstract

Section: Discussionmentioning

confidence: 98%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 98%

See 1 more Smart Citation

Aggressive rhabdoid meningioma with osseous, papillary and chordoma‐like appearance

Karabağlı

Yavaş

2014

Neuropathology

View full text Add to dashboard Cite

show abstract

“…Desmin immunopositivity is extremely unusual in meningiomas [7], and has been reported in five cases till date, all of which were rhabdoid meningiomas [8][9][10][11]. Perry et al described immunopositivity for cytokeratin and GFAP in the paranuclear inclusions in the first series of rhabdoid meningiomas [2].…”

Section: Discussionmentioning

confidence: 99%

Recurrent rhabdoid meningioma with lymph node, pulmonary and bone metastases: a diagnostic and therapeutic challenge

et al. 2016

View full text Add to dashboard Cite

Rhabdoid meningioma is a rare meningioma variant, classified as WHO grade III. Although this tumor is known for its aggressive behavior and poor prognosis, extracranial metastasis is rare. We report the rare case of a 31-year-old patient with rhabdoid meningioma which recurred several times despite gross total resection, radiation therapy, and gamma knife radiosurgery, and the last recurrence was associated with metastases to lungs, lymph node and bone. The patient showed no response to paclitaxel-carboplatin, or vincristine-cyclophosphamide-adriamycin chemotherapy, and succumbed to the disease. Metastases from rhabdoid meningioma prove to be a diagnostic challenge, and treatment for metastatic meningiomas is not optimized, thus necessitating documentation and interdisciplinary consensus on management protocols.

show abstract

“…rGB needs to be differentiated from other tumors of the CNS with rhabdoid morphology. Age of the patient is a useful factor to differentiate it from AT/RT, because mean age of presentation is 32.3 for rGB and 2.0 for AT/RT [17,18]. GFAP immunoexpression is negative in rhabdoid meningioma, whereas it is unequivocally positive, although focal and not extensive in rGB.…”

Section: Discussionmentioning

confidence: 99%

Magnetic Resonance Imaging Features of Rhabdoid Glioblastomas

et al. 2014

View full text Add to dashboard Cite

show abstract

Clinicopathological Analysis of Rhabdoid Meningiomas: Report of 12 Cases and a Systematic Review of the Literature

Cited by 21 publications

References 37 publications

Aggressive rhabdoid meningioma with osseous, papillary and chordoma‐like appearance

Aggressive rhabdoid meningioma with osseous, papillary and chordoma‐like appearance

Recurrent rhabdoid meningioma with lymph node, pulmonary and bone metastases: a diagnostic and therapeutic challenge

Magnetic Resonance Imaging Features of Rhabdoid Glioblastomas

Contact Info

Product

Resources

About