Clinicomicrobiological Evaluation of 2% Chitosan Mouthwashes on Dental Plaque

Abstract

Aim: This study was conducted to evaluate microbiological and clinical effects of a chitosan chlorhexidine (CH) mouthrinse on plaque control. Materials and methods:Subjects were divided into three groups. Group I included 15 subjects who used 0.2% chlorhexidine digluconate (CHX), group II included 15 subjects who used 2% chitosan (CH) solution, and group III involves 15 subjects who used 0.2% chlorhexidine/2% CH combination. Plaque index (PI), gingival index (GI), and probing depth (PD) were recorded at the baseline, on day 0, and after 4 days. Supragingival plaque samples were subjected for microbiological evaluation. Statistical analysis was done using statistical software IBM Statistical Package for the Social Sciences (SPSS), version 21. Results:Plaque index was lowest in group I at day 0, while it was highest in group III. At day 4, PI was highest in group II, while lowest in group III. Gingival index was lowest in group I and highest in group II at day 0, and lowest in group I and highest in group III at day 4. There was no statistical difference in Streptococcus mutans (S. mutans) Conclusion:Both chitosan and CH were found to be effective in controlling plaque. However, a combination of both provides even better results.Clinical significance: The present study showed that chitosan can be used as an antiplaque agent.

A Fresh Look at Mouthwashes—What Is Inside and What Is It For?

“… (1) Surfactant (may act as a solubiliser, emulsifier, emulsion stabiliser, detergent, wetting agent, foaming agent/defoamer and may possess antimicrobial features) [ 75 ]; (2) mucoadhesive film former (filmogenic agents) (it is suggested that they may act as a moisturiser, as dressing for wounds, to prevent dental plaque and stain formation, to prevent demineralisation, as a barrier to relieve pain in oral lesions such as aphthous ulcers, to improving the delivery and retention of actives) [ 27 , 76 , 77 , 78 , 79 , 80 , 81 , 82 , 83 ]; (3) remineralisation agent (to remineralise the demineralised tooth surface in dental caries or erosion as well as to prevent demineralisation, also in dentin hypersensitivity to obturate the dentinal tubules); (4) antimicrobial agent (an oral antiseptic, it may act as a preservative); (^) means it is discussed in the subsequent text. …”

Efficacy of Chitosan and Chlorhexidine Mouthwash on Dental Plaque and Gingival Inflammation: A Systematic Review

“…In Figures 2, 3, the review authors' judgments on each RoB-2 were shown as percentages across all included research, and the RoB-2 for each included study was presented as a summary. Among the three included studies, one study had low risk of bias [20] and two other studies has high over all risk of bias [21,22].…”

<p>Efektivitas antibakteri gel chitosan dengan berat molekul berbeda terhadap jumlah koloni bakteri Streptococcus mutans pada permukaan email sekitar braket ortodonti<p></p> Antibacterial effectiveness of chitosan gel with different molecular weights on the number of Streptococcus mutans colonies in the enamel surface around orthodontic bracket<p>

“…al., namun penelitian ini menggunakan konsentrasi obat kumur chitosan yang berbeda yaitu 1% dan chitosan berat molekul tinggi yang larut asam. 33 Berat molekul chitosan yang digunakan dalam penelitian ini memiliki batasan yang tidak jelas antara satu dengan yang lainnya sehingga memberikan hasil yang masih inkonsisten. Penelitian selanjutnya diharapkan dapat memberikan hasil yang lebih konsisten.…”