Clinical Significance of Nonsustained Ventricular Tachycardia on Stored Electrograms in Permanent Pacemaker Patients

Gabriels, James; Wu, Michael; Rosen, Lisa; Patel, Apoor; Goldner, Bruce

doi:10.1111/pace.12968

Cited by 10 publications

(17 citation statements)

References 22 publications

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“…Our results are from a representative, prospectively collected and contemporary cohort of pacemaker patients, and are in keeping with recently reported studies by Allen SM et al and Gabriels J et al, showing NSVT to be a benign finding. [7,8] Our data did not show a relationship between the presence of NSVT and significant LVSD, however the numbers of patients in the sub-groups were likely too small to reach statistical significance.…”

Section: Discussionmentioning

confidence: 60%

Prognostic Significance of Incidental Nonsustained Ventricular Tachycardia Detected on Pacemaker Interrogation

Jamil¹,

Mohammed²,

Gierula

et al. 2019

The American Journal of Cardiology

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Symptomatic sustained ventricular tachycardia is a life threatening arrhythmia requiring prompt treatment. However, the risk associated with asymptomatic nonsustained ventricular tachycardia (NSVT) detected on routine permanent pacemaker (PPM) interrogation in patients with known cardiac conduction disease is unknown. Our aim is to determine if asymptomatic NSVT detected on PPM interrogation is associated with increased mortality. As part of a prospective observational cohort study, 582 patients with long-term pacemakers were recruited at a tertiary cardiac centre, and followed for 4 ± 1.96 years (mean ± SD). At each subsequent pacemaker check, any symptoms and ventricular high-rate episodes (VHR) were recorded. We excluded 17 patients due to incomplete data. In, the remaining 565 patients (57% male, age 74.5 ± 19.2 years, left ventricular ejection fraction (LVEF) 50.0 ± 11.3 %), NSVT was found in 125 (22.1%) patients with a higher prevalence in males (65% v 54%; p=0.033). Those with NSVT were more likely to have had coronary artery disease (p=0.000) or previous myocardial infarction (p=0.015). After correction for baseline variables, NSVT had no impact on survival ((n=52 (42%) v n=162 (37%); log rank p= 0.331, hazard ratio (HR): 0.927, 95% CI: 0.678 to 1.268, p=0.697). In conclusion, asymptomatic NSVT identified on PPM interrogation does not appear to be associated with increased mortality, thus whether treatment to suppress this arrhythmia is of benefit remains unproven.

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Section: Discussionmentioning

confidence: 60%

Prognostic Significance of Incidental Nonsustained Ventricular Tachycardia Detected on Pacemaker Interrogation

Jamil¹,

Mohammed²,

Gierula

et al. 2019

The American Journal of Cardiology

View full text Add to dashboard Cite

show abstract

“…Moreover, a negative impact of NSVT was suggested in patients with reduced EF and those with coronary artery diseases, for whom an implantable cardioverter defibrillator would be mandatory . But, in the patients with a permanent implanted cardiac pacemaker, NSVT was not associated with an increased mortality …”

Section: Discussionmentioning

confidence: 99%

“…16 But, in the patients with a permanent implanted cardiac pacemaker, NSVT was not associated with an increased mortality. 17 Our aim was to decide whether NSVT had a significant influence on the prognosis of these NMD patients. This study has demonstrated that NSVT diagnosed with the Holter ECG was not significantly associated with patients' survival.…”

Section: Clinical Outcomes During Follow-upmentioning

confidence: 99%

Nonsustained ventricular tachycardia does not affect the prognosis of neuromuscular diseases: A preliminary and retrospective study

Kamihara

Yasuma

Murohara

2018

Journal of Arrhythmia

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BackgroundNonsustained ventricular tachycardia (NSVT) is sometimes observed in patients with neuromuscular diseases (NMDs). The aim of this study was to assess the role of NSVT in the survival prognosis of NMD patients.MethodsWe retrospectively analyzed the patients with NMDs who had undergone Holter ECG recordings at a single center between February and August 2012. Sixty‐eight patients were enrolled in this study. The 5 year follow‐up was assessed according to the cumulative event‐free rate.ResultsTwenty‐one patients died during the follow‐up, seven of whom died by cardiac death. The Kaplan–Meier survival curve that compared the patients with NSVT and those without NSVT indicated the NSVT was not related to the rate of all causes of death or cardiac death in those patients with NMDs. The survival curve was not significantly changed after the adjustment by age and ejection fraction.ConclusionNo significant correlations between NSVT and the prognosis in patients with NMDs were found.

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“…Tachycardias like atrial fibrillation and ventricular tachycardias are seen in patients who have undergone permanent pacemaker (PPM) implantations; however, supraventricular tachycardias in these patients are very rare. 1,2 A 20-year-old woman underwent PPM for repeated episodes of syncope owing to complete heart block in 2013. She underwent a dual-chamber PPM implantation and was 100% ventricular paced during regular follow-up.…”

Section: Introductionmentioning

confidence: 99%

Clinical Significance of Nonsustained Ventricular Tachycardia on Stored Electrograms in Permanent Pacemaker Patients

Abstract: In this cohort of patients, there was a high prevalence of HTN and while hypertensive subjects had a significantly higher NSVT burden, NSVT was not associated with an increased mortality.

Cited by 10 publications

References 22 publications

Prognostic Significance of Incidental Nonsustained Ventricular Tachycardia Detected on Pacemaker Interrogation

Prognostic Significance of Incidental Nonsustained Ventricular Tachycardia Detected on Pacemaker Interrogation

Nonsustained ventricular tachycardia does not affect the prognosis of neuromuscular diseases: A preliminary and retrospective study

High-rate episodes with simultaneous atrial and ventricular activation in a patient with permanent pacemaker implantation for complete heart block

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