Clinical profile of patients with obstructive jaundice: a surgeon’s perspectives

Abstract

Background: There are various causes of obstructive jaundice, choledocholithiasis– the commonest. Patients with obstructive jaundice usually present with complain of yellow skin and eyes, pale stools, dark coloured urine, jaundice, and pruritus.Abdominal pain often misleading for diagnosis. The objectives of the study were to study the clinical profile of patients with obstructive jaundice.Methods: The study included the patients clinically diagnosed as suffering from obstructive jaundice. Thorough history taking and clinical examination was done. Patients undergone for various laboratory investigations, and radiological evaluation.Results: A total 201 patients were included in the present study. Males are more affected (55.72%) as compared to females. Elder age groups (>65 years; and 55-65 years) were commonly affected. 58.71% of patients have malignant causes for development of obstructive jaundice as compared to benign causes in 41.29% of patients. Choledocholithiasis (30.35%) is the commonest cause of obstructive jaundice followed by carcinoma of pancreas (25.87%). Jaundice is the commonest symptom of presentation.Conclusions: Better understanding of the clinical profile in the patients with obstructive jaundice will facilitate appropriate management and lead to improved survival.

Perbedaan Kadar Bilirubin Serum antara Kelompok Patologi Neoplasma dan Non-neoplasma pada Ikterus Obstruktif

“…2 Penyebab ikterus obstruktif sangat bervariasi dan dapat dikelompokkan menjadi kelompok neoplasma dan non-neoplasma. 3 Penelitian oleh Khan ZA 4 menemukan bahwa penyebab ikterus obstruktif lebih banyak pada kelompok neoplasma (58,71%) dibanding kelompok nonneoplasma (41,29%). Lebih dari separuh pasien ikterus obstruktif akibat neoplasma meninggal dalam waktu tiga bulan setelah keluar dari rumah sakit dengan rerata kelangsungan hidup keseluruhan adalah 82 hari.…”

“…Penyakit ini umumnya melibatkan hati, sistem bilier, atau pankreas yang menyebabkan obstruksi dan gangguan aliran empedu ke duodenum. 4 Hasil penelitian ini menunjukkan bahwa koledokolitiasis menjadi penyebab tersering dari kelompok non-neoplasma dengan jumlah 18 kasus (85,7%) dan tumor di pankreas menjadi penyebab tersering untuk kelompok neoplasma dengan jumlah 12 kasus (57,1%).…”

Karakteristik Klinis Ikterus Obstruktif Disebabkan Tumor di RSUD Dr. H. Abdul Moeloek Lampung

“…Laki-laki lebih terpengaruh dibandingkan dengan perempuan. Sebanyak 58,71% pasien memiliki penyebab ganas untuk pengembangan penyakit ikterus obstruktif dibandingkan dengan penyebab jinak sebanyak 41,29% pasien (Khan, 2019). Pada penyakit ganas, gejala yang paling umum adalah penyakit kuning pada 100% pasien diikuti oleh hilangnya nafsu makan dan berat pada pada 90% pasien.…”

Frequency of common bile duct strictures in patients presenting with obstructive jaundice in Ayub teaching hospital

“…Obstructive jaundice is defined as conjugated hyperbilirubinemia secondary to obstruction to the flow of bile from the liver. [1] It is caused by obstruction, blockage and/or compression of common bile duct (CBD) and/or biliary tract that leads to incomplete excretion of bile into the intestine. [2] Patients complains of abdominal pain, yellow discoloration of skin and/or eyes, pale stools, dark colored urine, nausea, vomiting and itching.…”