Clinical profile of babies with meconium stained amniotic fluid

Ranee, Defairlin; Phirke, Deepa Sachin

doi:10.18203/2320-6012.ijrms20174116

Cited by 3 publications

(3 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…are so many predisposing risk factors that promote the passage of meconium into the amniotic fluid in utero like utero-placental insufficiency, maternal hypertension, cord around neck, oligohydramnios, diabetes mellitus, heavy smoking, post-term pregnancy and intra uterine growth restriction, ante-partum haemorrhage and anemia. 4 Outcome of MAS mainly depends on type of meconium that is thin or thick, amount of meconium aspirated and perinatal care offered to the baby during delivery, planned team approach to MSAF babies, proper perinatal care has changed the morbidity and mortality of MAS. 5 The aim of the study study was to investigate clinical profile of MAS, its risk factors and severity among newborns at our institute.…”

Section: Introductionmentioning

confidence: 99%

A study of profile of meconium aspiration syndrome in relation with birth weight and gestational age of newborns and their immediate outcome

Kalra¹,

Wasim²

2021

Int J Contemp Pediatr

View full text Add to dashboard Cite

Background: Meconium aspiration syndrome (MAS) is one of the common causes of neonatal respiratory distress. Overall frequency of meconium stained amniotic fluid (MSAF) ranges between 5 to 25%.Methods: Observational study was conducted on 96 newborns over a period of one year in the department of pediatrics, Himalayan Institute of Medical Sciences, Dehradun, Uttarakhand. All newborns, inborns and outborns with MSAF admitted in NICU of our hospital were taken. Results: Out of 876 babies those had MSAF, 96 babies developed MAS with 10.95% incidence. Common maternal risk factors noted with MAS was maternal diabetes mellitus in 11 (15.71%) cases. Babies born via LSCS developed MAS in 51 (53.12%) and in babies delivered vaginally 45 (46.87%). MAS occurred mainly in term with mean gestational age of 38 weeks with SD of 1.85 weeks. The mean birth weight of newborns with MAS was 2794 g with 524 g SD. Most common complication was birth asphyxia in 36 (37.5%). Mortality occurred in 11 (11.4%). Mean gestational age and birth weight of mortality in MAS was 38 weeks with 2.5 weeks SD and 2800 g with 723 g SD respectively. Statistically significant association noted between mortality due to MAS and birth weight as p value<0.05, but no significant association noted between mortality and gestational age.Conclusions: MAS is a common cause of respiratory distress in newborns born through MSAF. With judicious use of available modes of ventilation and adjunctive therapies, infants with even the most severe MAS can usually be supported through the disease, with an acceptable burden of short-and long-term morbidity.

show abstract

Section: Introductionmentioning

confidence: 99%

A study of profile of meconium aspiration syndrome in relation with birth weight and gestational age of newborns and their immediate outcome

Kalra¹,

Wasim²

2021

Int J Contemp Pediatr

View full text Add to dashboard Cite

show abstract

“…16 About 5% of the babies born through meconium stained amniotic fluid develop meconium aspiration syndrome and the mortality rate of these babies vary from 4-7%. 17 In deliveries complicated with MSAF, there is an increased risk of caesarean section, chorioamnionitis and puerperal sepsis along with higher morbidity and mortality in mother while the unfavorable outcomes in neonate include increased risks of birth asphyxia and fetal distress, low Apgar scores, increased incidence of neonatal intensive care unit (NICU) admission, meconium aspiration syndrome and early neonatal death. 18,19 Meconium stained amniotic fluid is really alarming for both obstetrician and pediatrician and thus taking the risks into consideration, this study was done to identify the associated risk factors of meconium stained deliveries and compare the perinatal outcome in deliveries complicated by meconium staining versus clear liquor.…”

Section: Introductionmentioning

confidence: 99%

Study of risk factors and perinatal outcome in meconium stained deliveries from a district of Uttar Pradesh, India

Rathoria

Bansal

et al. 2018

Int J Reprod Contracept Obstet Gynecol

View full text Add to dashboard Cite

Background: The objective is to identify the risk factors of Meconium stained deliveries and evaluate the perinatal outcomes in Meconium Stained deliveries.Methods: This prospective observational study included those pregnant women who had completed 37 weeks of gestation, with singleton pregnancies with cephalic presentations and with no known fetal congenital anomalies. Among these, we selected 110 cases with Meconium stained amniotic fluid and they were compared with 110 randomly selected controls.Results: Regular antenatal visits were seen in 22.73 % of the cases while 77.27% cases had no previous visit. Majority of cases were primigravida and gestational ages of >40 weeks was seen in 55.45 % cases. 19.09% cases had meconium staining among pregnancies complicated with pregnancy induced hypertension, as compared to those among controls (5.45%). Fetal heart rate abnormalities were seen in 29.09% cases, and statistically significant fetal bradycardia was seen in cases. Caesarean section rates were nearly double in cases (54.55%). Poor perinatal outcome was found in cases as seen in results by low Apgar score (<7) at 1 minute and 5-minute, higher incidence of birth asphyxia, Meconium Aspiration Syndrome and increased NICU admission as compared to that among controls.Conclusions: Meconium stained amniotic fluid is more commonly associated with higher gestational age >40 weeks, pregnancy induced hypertension and fetal bradycardia, increased cesarean section rates, low APGAR score and higher incidence of birth asphyxia and NICU admissions. Meconium aspiration syndrome was associated with early neonatal death.

show abstract

“…There is a significant association between low APGAR score at 1 min and the development of MAS which is similar to the present study. 16 The study done by Viraraghavan VR et al, showed that 3% of vigorous babies and 21.7% of nonvigorous babies developed MAS, which showed statistical significance between non-vigorous neonates and development of MAS (p <0.001). 11 The study done by Gurmeet et al showed that 33% of the cases with MAS expired and 67% of cases with MAS were discharged, which is almost similar to the present study.…”

Section: Discussionmentioning

confidence: 92%

Study of respiratory complications and outcome in meconium stained deliveries

Shukla

Swapna

2019

Int J Contemp Pediatr

View full text Add to dashboard Cite

Background: To study the development of respiratory complications in the form of meconium aspiration syndrome (MAS), persistent pulmonary hypertension of newborn (PPHN), pulmonary hemorrhage and pneumothorax in neonates born through meconium stained liquor.Methods: It was a prospective study conducted during the period of February to October 2018. All live babies associated with meconium stained liquor were included.Results: Total 606 neonates with meconium stained amniotic fluid (MSAF) were enrolled. Chance of meconium passage was more after 37wk of gestation, in birth weight >2.5 kg and in AGA babies. The rate of LSCS was higher in MSAF group. MAS developed in 28% cases, out of which 42.9% expired. PPHN developed in 6.9% cases, out of which 80% expired. 100% mortality was there in babies with pulmonary hemorrhage. Apgar scores <7 is significantly associated with the development of respiratory complications. 22.8% of vigorous babies and all non-vigorous babies developed respiratory complications showing statistical significance with P-value of <0.00001. Mortality in MSAF was 12%. All babies who expired had severe meconium aspiration syndrome. 83.9% of the patients stayed for <7 days in the hospital. All of the expiry except one occurred within 7 days of life due to development of respiratory complications.Conclusions: MSAF is associated with the development of respiratory complications and mortality in neonates. Non-vigorous babies and the babies with Apgar scores <7 at birth are more prone to developing respiratory complications. Most of the MSAF babies were discharged and mortality was more in patients with respiratory complications.

show abstract

Clinical profile of babies with meconium stained amniotic fluid

Cited by 3 publications

References 4 publications

A study of profile of meconium aspiration syndrome in relation with birth weight and gestational age of newborns and their immediate outcome

A study of profile of meconium aspiration syndrome in relation with birth weight and gestational age of newborns and their immediate outcome

Study of risk factors and perinatal outcome in meconium stained deliveries from a district of Uttar Pradesh, India

Study of respiratory complications and outcome in meconium stained deliveries

Contact Info

Product

Resources

About