Clinical Presentations of Myasthenia Gravis

Prevalence and risk factors of myasthenia gravis recurrence post-thymectomy

“…Neurosciences J 2021; Vol. 26 (1) www.nsj.org.sa immediate post-operative outcomes of thymectomy in individuals with MG, (iv) Studies on post-thymectomy MG which developed in individuals with thymoma who had no preceding presentation of myasthenia gravis, (v) Studies with a sample size less than 10. Also, case reports, conference abstracts, editorials, commentaries, review articles and duplicate publications were deemed ineligible.…”

“…This finding further lends credence to a recent report of a randomised controlled trial which demonstrated the additional benefit of surgical treatment (thymectomy) relative to pharmacological therapy alone for the Neurosciences J 2021; Vol. 26 (1) www.nsj.org.sa management of individuals with MG. 9 This indicates that thymectomy is an important management strategy but additional care needs to be given in order to prevent recurrence among affected patients.…”

“…MG recurrence post-thymectomy ... Alqarni et al www.nsj.org.sa M yasthenia gravis (MG) a rare clinical condition characterized by autoimmune abnormalities is also the commonest neuromuscular junction (NMJ) disorder. 1 Its pathophysiology involves the production of abnormal antibodies which binds to nicotinic acetylcholine receptors at the NMJ of skeletal muscles leading to alteration and damage of the NMJ. [1][2] The disease is common in young women, however, another peak in incidence may occur at the 6th or 7th decade of life mainly in men in some population; and it may exhibits no sex preference in others.…”

“…1 Its pathophysiology involves the production of abnormal antibodies which binds to nicotinic acetylcholine receptors at the NMJ of skeletal muscles leading to alteration and damage of the NMJ. [1][2] The disease is common in young women, however, another peak in incidence may occur at the 6th or 7th decade of life mainly in men in some population; and it may exhibits no sex preference in others. 2 Clinically, patients with MG develop varying levels of skeletal muscle weakness affecting the ocular, bulbar, oculo-bulbar system, respiratory system, and the extremities.…”

“…2 Clinically, patients with MG develop varying levels of skeletal muscle weakness affecting the ocular, bulbar, oculo-bulbar system, respiratory system, and the extremities. 1 The pattern and course of MG is complex, varying from early remission to acute exacerbation and even death. 3 Previous research has revealed a strong relation between MG and disorders affecting the thymus.…”