Abstract:Successful treatment of hyperthyroidism is predicated upon an understanding of the pharmacology of antithyroid drugs as well as upon a knowledge of their effects on pathways of thyroidal iodide metabolism. Research into the relationship between chemical structure and biologic action of numerous antithyroid compounds has served as a basis for their classification and for selection of those of greatest potency for clinical trial. Biochemical determination of the site and mode of action of compounds affecting thy… Show more
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.