Clinical Pattern of Vitiligo Amongst Indians

Abstract

Vitiligo incidence in the series was 14 per thousand. The affliction of the younger subjects was frequent, the mean value of age at onset being 24.25 years. Both the sexes were affected and there was no significant difference between the two. The duration of the disease had wide variations, majority reporting in the course of one year. The emotional undertones and the ocurrence of the disease amongst family links were observed as provocating factors in some cases. Ivory white macules associated sometimes with erythematous tinge, leucotrichiae and islets of pigmentation were classic. The lower extremities were frequently involved, followed by face and other parts of the body. The disease was largely progressive, though in a few it was stationary. Vitiligo vulgaris was its commonest variant, followed by areata, zosteriformis, mucosae and acrofacialis. The associations namely diabetes mellitus, liver diseases and others were recorded. The occurrence of myasthenia gravis and trigeminal neuralgia in vitiligo was interesting. Its association on the basis of autoimmunity is brought out. The importance of the clinical parameters in anticipating the prognosis after psoralen therapy are discussed.

The Vitiligo in Senegal

“…Our study was limited by its short duration which did not allow us to evaluate the lesions' outcome on the long run. The 1.2% frequency is close to the one registered by Sehgal et al in India [5] and the frequency of 1 to 2% reported worldwide [6]. The female predominance was also observed by Kar [7] who noted 51.6% of women against 48.35% of men.…”

Vitiligo: A comprehensive overview

“…16,17 The mean age of onset is earlier in those with a positive family history, 2,18 which ranges from 7.7% to more than 50%. 2,17,[19][20][21][22][23] Vitiligo is significantly more prevalent in young women ( # 30 years of age) than young men. 1,13,24,25 The peak in females occurs in the first decade of life.…”

A pilot study assessing the role of 25 hydroxy vitamin D levels in patients with vitiligo vulgaris

“…1 Vitiligo is commonly associated with systemic autoimmune conditions, including hypothyroidism and hyperthyroidism, 2 diabetes mellitus, 3 and Sjögren's syndrome. 4 Many autoimmune conditions have been associated with reduced vitamin D levels, including rheumatoid arthritis, diabetes mellitus, and multiple sclerosis.…”